SCHEMBL3676122

SCHEMBL3676122

OCCCCCCCCSSCCCCCCCCO

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.37
GPR84 Q9NQS5 1/20 0.36
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
KDM4E B2RXH2 1/20 0.35
CA2 P00918 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
MIF P14174 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18655487 1.00 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL28691524 1.00 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL27989892 1.00 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL7902914 1.00 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL3723747 1.00 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL2458373 1.00 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL29055449 1.00 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL3579746 1.00 LMNA (0.42) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL3679045 0.96 SMN1; SMN2 (0.39) LMNAALDH1A1TSHRHSD17B10MEN1
Ethylene SCHEMBL7913495 0.94 LMNA (0.38) LMNAALDH1A1TSHRHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3211017-A1 POLYURETHANE Compagnie Générale des Etablissements Michelin (FR) 2017-08-30 EP disclosed
EP-2115033-B1 POLYURETHANE MICHELIN & CIE (FR) 2017-05-17 EP disclosed
US-20130287982-A1 POLYURETHANE MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-10-31 US disclosed
US-8512834-B2 Polyurethane COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2013-08-20 US disclosed
US-20100047493-A1 Polyurethane COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2010-02-25 US disclosed
EP-2115033-A1 POLYURETHANE Societe de Technologie Michelin (FR) 2009-11-11 EP disclosed
WO-2008077151-A1 POLYURETHANE SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-06-26 WO disclosed
EP-0552376-B1 PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE NIPPON CATALYTIC CHEM IND (JP) 1999-01-13 EP disclosed
US-5391665-A Catalyzed polymerization in the presence of a dihydroxypolysulfide compound NIPPON SHOKUBAI CO., LTD. (JP) 1995-02-21 US disclosed
EP-0552376-A1 PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE NIPPON SHOKUBAI CO., LTD. (JP) 1993-07-28 EP disclosed