Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201865 | 0.89 | SRD5A2 (0.55) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7166968 | 0.88 | SRD5A2 (0.54) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5483649 | 0.82 | SRD5A2 (0.57) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL1179548 | 0.82 | SRD5A2 (0.53) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30453001 | 0.80 | SRD5A2 (0.56) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7171723 | 0.80 | TUBB1 (0.50) | SRD5A2MEN1KMT2AL3MBTL1 | |
| SCHEMBL8362532 | 0.80 | SRD5A2 (0.55) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5108340 | 0.79 | SRD5A2 (0.55) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2002039 | 0.77 | SRD5A2 (0.55) | SRD5A2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2002036 | 0.77 | SRD5A2 (0.55) | SRD5A2MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173174-A1 | FARNESOID X RECEPTOR AGONISTS | GlaxoSmithKline LLC (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009005998-A1 | FARNESOID X RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-01-08 | — | — | WO | disclosed |