Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166968 | 0.93 | SRD5A2 (0.54) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3676129 | 0.89 | SRD5A2 (0.51) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5483649 | 0.86 | SRD5A2 (0.57) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1179548 | 0.86 | SRD5A2 (0.53) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL30453001 | 0.84 | SRD5A2 (0.56) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7171723 | 0.84 | TUBB1 (0.50) | SRD5A2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2492694 | 0.84 | HDAC1 (0.47) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2492696 | 0.84 | HDAC1 (0.47) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8362532 | 0.84 | SRD5A2 (0.55) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5108340 | 0.83 | SRD5A2 (0.55) | SRD5A2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544821-B1 | INDOLE DERIVATIVES AS ANTIALLERGY AND ANTIINFLAMMATORY AGENTS | PFIZER (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5290788-A | Indole derivatives as antiallergy and antiinflammatory agents | PFIZER INC. (US) | 1994-03-01 | — | — | US | disclosed |