SCHEMBL3676238

SCHEMBL3676238

C=C(C)C(=O)C1CC2C=CC1C2

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
LMNA P02545 1/20 0.52
ALDH1A1 P00352 5/20 0.39
THRB P10828 1/20 0.38
HPGD P15428 1/20 0.34
EPHX2 P34913 3/20 0.33
POLB P06746 3/20 0.33
KMT2A Q03164 2/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 3/20 0.32
APEX1 P27695 2/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
ESR2 Q92731 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HSD11B1 P28845 2/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9695778 0.84 KDM4E (0.55) KDM4ELMNAALDH1A1THRBHPGD
SCHEMBL14822849 0.79 KDM4E (0.59) KDM4ELMNAALDH1A1THRBHPGD
SCHEMBL3376067 0.79 KDM4E (0.48) KDM4ELMNAALDH1A1THRBHPGD
SCHEMBL190395 0.79 KDM4E (0.48) KDM4ELMNAALDH1A1THRBHPGD
SCHEMBL11689296 0.79 KDM4E (0.59) KDM4ELMNAALDH1A1THRBHPGD
SCHEMBL301403 0.79 KDM4E (0.59) KDM4ELMNAALDH1A1THRBHPGD
Water SCHEMBL7734213 0.78 KDM4E (0.57) KDM4ELMNAALDH1A1THRBHPGD
SCHEMBL5892403 0.74 KDM4E (0.63) KDM4ELMNAALDH1A1THRBHPGD
SCHEMBL600202 0.74 KDM4E (0.53) KDM4ELMNAALDH1A1THRBHPGD
SCHEMBL5070801 0.73 ALDH1A1 (0.44) KDM4ELMNAALDH1A1THRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200181381-A1 RUBBER COMPOSITION HAVING COATING FILM AFFINITY AND EXTERNAL DIAPHRAGM FOR RAILROAD CARS SUMITOMO RIKO COMPANY LIMITED (JP) 2020-06-11 US disclosed
US-7776410-B2 aromatic polyester amide liquid crystal resin, ethylene-glycidyl methacrylate copolymers; improved draw down resistance and uniform wall thickness without damaging low gas permeability; blow molded vessels, tubular films, liners, tubes or pipes POLYPLASTICS CO. LTD. (JP) 2010-08-17 US disclosed
EP-1195244-B1 Rubber hose TOKAI RUBBER IND LTD (JP) 2009-08-26 EP disclosed
US-20080286510-A1 Resin Composition for Extrusion Molding and Extrusion-Molded Article POLYPLASTICS CO., LTD. (JP) 2008-11-20 US disclosed
EP-1813650-A1 RESIN COMPOSITION FOR EXTRUSION MOLDING AND EXTRUDED PRODUCT Polyplastics Co., Ltd. (JP) 2007-08-01 EP disclosed
EP-1195403-B1 Rubber composition TOKAI RUBBER IND LTD (JP) 2004-12-15 EP disclosed
US-20040146676-A1 Flexible hose TOKAI RUBBER INDUSTRIES, LTD. (JP) 2004-07-29 US disclosed
US-6619329-B2 Laminate including an ethylene-propylene-diene terpolymer or ethylene-propylene copolymer, peroxide vulcanizing agent, a resorcinol resin, melamine resin, and a polyamide or an ethylene-vinyl alcohol copolymer, or a metal TOKAI RUBBER INDUSTRIES, LTD. (JP) 2003-09-16 US disclosed
US-6552128-B2 Ethylene-propylene-diene terpolymer and/or an ethylene-propylene copolymer, a peroxide vulcanizing agent, a resorcinol compound and a melamine resin; superior adhesion force without a coating of adhesive TOKAI RUBBER INDUSTRIES, LTD. (JP) 2003-04-22 US disclosed
US-20020074050-A1 Hose SUMITOMO RIKO COMPANY LIMITED (JP) 2002-06-20 US disclosed
US-20020068797-A1 Rubber composition SUMITOMO RIKO COMPANY LIMITED (JP) 2002-06-06 US disclosed
EP-1195244-A1 Rubber hose Tokai Rubber Industries, Ltd. (JP) 2002-04-10 EP disclosed
EP-1195403-A2 Rubber composition Tokai Rubber Industries, Ltd. (JP) 2002-04-10 EP disclosed