SCHEMBL3676323

SCHEMBL3676323

CC(C)(C)c1cc(CCC(=O)OCC2CO2)cc(C(C)(C)C)c1O

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
GAA P10253 3/20 0.49
MGLL Q99685 5/20 0.45
PKM P14618 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9410263 0.94 KMT2A (0.47) KMT2AMEN1GAAMGLLPKM
SCHEMBL11771629 0.84 GAA (0.51) KMT2AMEN1GAAPKMHTT
SCHEMBL13121607 0.84 MGLL (0.49) MGLL
SCHEMBL12670428 0.83 MGLL (0.41) KMT2AMEN1MGLL
SCHEMBL858494 0.82 GAA (0.60) KMT2AMEN1GAAPKMHTT
SCHEMBL208761 0.82 GAA (0.60) KMT2AMEN1GAAPKMHTT
Cyclohexane SCHEMBL676099 0.81 GAA (0.56) KMT2AMEN1GAAPKMHTT
Methane SCHEMBL5968168 0.81 GAA (0.59) KMT2AMEN1GAAPKMHTT
Ethane SCHEMBL9814026 0.81 GAA (0.59) KMT2AMEN1GAAPKMHTT
SCHEMBL8660921 0.80 GAA (0.55) KMT2AMEN1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947831-B2 Sulfoxides or sulfones grafted onto polymers BASF SE Ludwigshafen (DE) 2011-05-24 US disclosed
US-7807757-B2 stabilizing and at the same time phase compatibilizing plastics or plastic compositions by incorporating maleic anhydride or acrylic acid grafted copolymer or terpolymer (styrene/butadiene/styrene block copolymer grafted with maleic anhydride) obtained by reacting with a benzotriazole compound CIBA SPECIALTY CHEMICALS CORP. (US) 2010-10-05 US disclosed
US-20080051521-A1 Functionalized polymers PFAENDNER RUDOLF 2008-02-28 US disclosed
US-7300978-B2 Functionalised polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-11-27 US disclosed
US-20070015870-A1 Sulfoxides or sulfones grafted onto polymers CIBA CORPORATION 2007-01-18 US disclosed
US-20070015870-A1 Sulfoxides or sulfones grafted onto polymers CIBA CORPORATION 2007-01-18 US disclosed
US-7160955-B2 Sulfoxides or sulfones grafted onto polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-09 US disclosed
US-7160955-B2 Sulfoxides or sulfones grafted onto polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-09 US disclosed
US-20040167291-A1 Functionalised polymers PFAENDNER RUDOLF (DE) 2004-08-26 US disclosed
US-20020123577-A1 Functionalised polymers PFAENDNER RUDOLF (DE) 2002-09-05 US disclosed
US-6362278-B1 STABILIZATION USING STERIC HINDERED AMINE COMPOUND CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-26 US disclosed
EP-0935619-B1 FUNCTIONALISED POLYMERS CIBA SC HOLDING AG (CH) 2001-06-20 EP disclosed
EP-0935619-A1 FUNCTIONALISED POLYMERS Ciba SC Holding AG (CH) 1999-08-18 EP disclosed
WO-1998018830-A1 FUNCTIONALISED POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-05-07 WO disclosed
EP-0583971-A1 Piperidine derivatives SANKYO COMPANY LIMITED (JP) 1994-02-23 EP disclosed