Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367841 | 0.87 | TP53 (0.39) | TP53CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL367968 | 0.87 | TP53 (0.42) | TP53CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL15092108 | 0.86 | TP53 (0.40) | TP53CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL368701 | 0.86 | TP53 (0.40) | TP53CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL367643 | 0.86 | TP53 (0.39) | TP53CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL367233 | 0.85 | TP53 (0.39) | TP53CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL368957 | 0.83 | TP53 (0.38) | TP53CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL15101329 | 0.78 | ENPP2 (0.39) | TP53LMNACYP2C9CYP2C19HTR2A | |
| SCHEMBL10070053 | 0.78 | SMN1; SMN2 (0.42) | TP53LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL369125 | 0.78 | PRMT5 (0.41) | YAP1CYP2D6CYP2C9PDE4BPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593460-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | Avexa Limited (AU) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012006680-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | AVEXA LIMITED (AU) | 2012-01-19 | — | — | WO | disclosed |