Sugi Predict

Sugi Predict / Compounds / SCHEMBL3676474

SCHEMBL3676474

SCHEMBL3676474

CC(C)(C)OC(=O)NC(COS(C)(=O)=O)CC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA7 P43166 2/20 0.39
▸ ATM Q13315 1/20 0.39
▸ CYP2D6 P10635 1/20 0.38
▸ CTSK P43235 11/20 0.37
▸ CTSS P25774 8/20 0.37
▸ SYK P43405 1/20 0.36
▸ CTSL P07711 1/20 0.35
▸ CTSB P07858 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ CA12 O43570 2/20 0.34
▸ CA14 Q9ULX7 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29255184 1.00 CA1 (0.39) CA1CA2CA7ATMCYP2D6
SCHEMBL22409473 1.00 CA1 (0.39) CA1CA2CA7ATMCYP2D6
SCHEMBL2013068 0.89 CA1 (0.44) CA1CA2CA7ATMCYP2D6
SCHEMBL15074927 0.88 CYP2D6 (0.48) CA1CA2CA7ATMCYP2D6
SCHEMBL15071343 0.88 CA1 (0.39) CA1CA2CA7ATMCYP2D6
SCHEMBL2862093 0.87 CA12 (0.42) CA1CA2CA7ATMCYP2D6
SCHEMBL19014800 0.87 CA12 (0.42) CA1CA2CA7ATMCYP2D6
SCHEMBL25291413 0.86 ATM (0.37) CA1CA2CA7ATMCYP2D6
SCHEMBL2909087 0.86 ATM (0.37) CA1CA2CA7ATMCYP2D6
SCHEMBL25254058 0.86 ATM (0.37) CA1CA2CA7ATMCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307534-A LTA4H inhibitors and uses thereof 上海海雁医药科技有限公司 2024-07-09 — — CN disclosed
US-11111259-B2 Acylsulfonamide derivatives for treating senescence-associated diseases and disorders UNITY BIOTECHNOLOGY, INC. (US) 2021-09-07 — — US disclosed
US-20200291050-A1 ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS UNITY BIOTECHNOLOGY, INC. 2020-09-17 — — US disclosed
US-8410150-B2 Inhibitors of carnitine palmitoyltransferase and treating cancer UNIVERSITY HEALTH NETWORK (CA) 2013-04-02 — — US disclosed
US-20100105900-A1 INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER UNIVERSITY HEALTH NETWORK 2010-04-29 — — US disclosed
WO-2008109991-A1 INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER UNIVERSITY HEALTH NETWORK (CA) 2008-09-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105900-A1 INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER CPT1A, CPT1B, CPT2 CA1 1983/4885CA2 1295/4885CA7 1327/4885
US-11111259-B2 Acylsulfonamide derivatives for treating senescence-associated diseases and disorders ACAT1, ARSA, GLA CA1 4448/4885CA2 3873/4885CA7 2628/4885
US-20200291050-A1 ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS ACAT1, ARSA, GLA CA1 4448/4885CA2 3873/4885CA7 2628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.