Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.39 |
| ▸ | F7 | P08709 | 4/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841872 | 0.71 | TRPV4 (0.42) | — | |
| SCHEMBL28785671 | 0.70 | F10 (0.38) | F10PRSS1F7F2 | |
| SCHEMBL28785673 | 0.70 | F10 (0.38) | F10PRSS1F7F2 | |
| SCHEMBL27776651 | 0.69 | F10 (0.34) | F10PRSS1F2 | |
| SCHEMBL27776654 | 0.67 | F10 (0.36) | F10PRSS1F7F3F2 | |
| SCHEMBL27776667 | 0.67 | F2 (0.59) | PRSS1PRSS2PRSS3F7F2 | |
| SCHEMBL27776650 | 0.66 | F2 (0.42) | F10F7F2 | |
| SCHEMBL840919 | 0.66 | FLT1 (0.45) | — | |
| SCHEMBL27776662 | 0.66 | F2 (0.47) | F10PRSS1PRSS2PRSS3F7 | |
| SCHEMBL3685510 | 0.65 | F2 (0.41) | F10PRSS1PRSS2PRSS3F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176223-A1 | MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY | Sanofi-Aventis (FR) | 2010-04-21 | — | — | EP | disclosed |
| CN-101687797-A | Malonamide derivatives with antithrombotic activity | SANOFI AVENTIS | 2010-03-31 | — | — | CN | disclosed |
| WO-2009007015-A1 | MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY | SANOFI-AVENTIS (FR) | 2009-01-15 | — | — | WO | disclosed |