Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671168 | 1.00 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3679421 | 1.00 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3677010 | 1.00 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3678546 | 1.00 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3673223 | 0.84 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3676429 | 0.84 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3677497 | 0.84 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3687029 | 0.84 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3679042 | 0.84 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL5164702 | 0.81 | ALDH1A1 (0.46) | SLC6A4SLC6A2SLC6A3ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030027869-A1 | Amine compounds and inhibiting neurotransmitter reuptake | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2003-02-06 | — | — | US | claimed |
| US-20100168246-A1 | AMINE COMPOUNDS AND INHIBITING NEUROTRANSMITTER REUPTAKE | RICHELSON ELLIOTT | 2010-07-01 | — | — | US | disclosed |
| US-20080275272-A1 | AMINE COMPOUNDS AND INHIBITING NEUROTRANSMITTER REUPTAKE | RICHELSON ELLIOTT | 2008-11-06 | — | — | US | disclosed |
| US-6914080-B2 | Amine compounds and inhibiting neurotransmitter reuptake | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2005-07-05 | — | — | US | disclosed |
| US-6700018-B2 | 3-HYDROXY-2-(2-NAPHTHYL)PENTYLAMINE DERIVATIVES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2004-03-02 | — | — | US | disclosed |
| US-20030027869-A1 | Amine compounds and inhibiting neurotransmitter reuptake | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2003-02-06 | — | — | US | disclosed |