Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 18/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601921 | 1.00 | DGAT1 (0.72) | DGAT1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL601103 | 1.00 | DGAT1 (0.72) | DGAT1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL601104 | 1.00 | DGAT1 (0.72) | DGAT1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL602148 | 0.88 | DGAT1 (0.64) | DGAT1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL602149 | 0.88 | DGAT1 (0.64) | DGAT1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL3671468 | 0.86 | DGAT1 (0.80) | DGAT1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL602580 | 0.85 | DGAT1 (0.78) | DGAT1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL603709 | 0.85 | DGAT1 (0.78) | DGAT1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL3672639 | 0.85 | DGAT1 (0.78) | DGAT1MEN1NPC1RAB9AKMT2A | |
| Bicarbonate SCHEMBL15655199 | 0.84 | DGAT1 (0.76) | DGAT1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391611-B1 | THIADIAZOLE AND OXADIAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-04-30 | — | — | EP | disclosed |
| EP-2391611-A1 | THIADIAZOLE AND OXADIAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010086551-A1 | THIADIAZOLE AND OXADIAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-08-05 | — | — | WO | disclosed |