SCHEMBL3676950

SCHEMBL3676950

FC(F)(F)C(c1cccc(Br)c1)(c1cccc(Br)c1)C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA5A P35218 1/20 0.53
CA9 Q16790 1/20 0.53
ALDH1A1 P00352 3/20 0.40
KIF11 P52732 1/20 0.40
MAPK1 P28482 2/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
CTSL P07711 1/20 0.36
TSHR P16473 2/20 0.35
KDM1A O60341 2/20 0.34
C1S P09871 1/20 0.33
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
PARP1 P09874 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
MPO P05164 1/20 0.33
MTOR P42345 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10291600 0.82 CA1 (0.53) CA1CA2CA5ACA9ALDH1A1
SCHEMBL30896627 0.82 CA1 (0.53) CA1CA2CA5ACA9ALDH1A1
SCHEMBL5349272 0.82 CA1 (0.53) CA1CA2CA5ACA9ALDH1A1
SCHEMBL29824423 0.81 CA1 (0.57) CA1CA2CA5ACA9ALDH1A1
SCHEMBL4661 0.81 CA1 (0.57) CA1CA2CA5ACA9ALDH1A1
SCHEMBL13623124 0.81 CA1 (0.57) CA1CA2CA5ACA9ALDH1A1
SCHEMBL1504913 0.79 CA1 (0.55) CA1CA2CA5ACA9ALDH1A1
SCHEMBL1504972 0.79 CA1 (0.55) CA1CA2CA5ACA9ALDH1A1
SCHEMBL15122792 0.78 CA1 (0.50) CA1CA2CA5ACA9ALDH1A1
SCHEMBL11717644 0.78 CA1 (0.50) CA1CA2CA5ACA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
US-7615300-B2 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology The Board of Regents University and Community College System of Nevada on Behalf of the University of Nevada (US) 2009-11-10 US disclosed
US-7615300-B2 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology The Board of Regents University and Community College System of Nevada on Behalf of the University of Nevada (US) 2009-11-10 US disclosed
US-20070048579-A1 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology Board of Regents University and Community College System of Nevada 2007-03-01 US disclosed
US-20070048579-A1 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology Board of Regents University and Community College System of Nevada 2007-03-01 US disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
EP-1245554-B1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORP (JP) 2005-01-26 EP disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-6794480-B2 POLYARYLENE-BASED COPOLYMER USEFUL AS PROTON-CONDUCTIVE MEMBRANE WHICH CAN BE USED AS ELECTRON FOR PRIMARY BATTERY, ELECTROLYTE FOR SECONDARY BATTERY, HIGH MOLECULAR SOLID ELECTROLYTE FOR FUEL CELL JSR CORPORATION (JP) 2004-09-21 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020177656-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR CORPORATION (JP) 2002-11-28 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
EP-1245554-A1 Monomer containing electron-withdrawing group and electron-donative group, and copolymer and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed
US-4814472-A Diethynylated diphenyl hexafluoropropanes HUGHES AIRCRAFT COMPANY (US) 1989-03-21 US disclosed
EP-0092310-B1 BIS(HALOPHENYL)HEXAFLUOROPROPANES AND PROCESS FOR MAKING THE SAME Hughes Aircraft Company (US) 1985-07-24 EP disclosed
US-4503254-A HALOGENATION OF HYDROXY PRECURSOR WITH TRIPHENYLPHOSPHINE DIHALIDE HUGHES AIRCRAFT COMPANY (US) 1985-03-05 US disclosed
EP-0092310-A1 Bis(halophenyl)hexafluoropropanes and process for making the same Hughes Aircraft Company (US) 1983-10-26 EP disclosed