SCHEMBL3677529

SCHEMBL3677529

COc1c(C(C)(C)c2cccc3c2C([Si](C)(C)C)c2ccccc2-3)cc(C)cc1[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3675098 0.92
SCHEMBL3677356 0.89
SCHEMBL3680374 0.89 TNFRSF1A (0.31)
SCHEMBL3683683 0.81
SCHEMBL3677350 0.81 CA1 (0.32)
SCHEMBL3678067 0.80 TNFRSF1A (0.30)
SCHEMBL3683118 0.79 JAK2 (0.31)
SCHEMBL3676820 0.78 NR3C1 (0.35)
SCHEMBL3675854 0.76
SCHEMBL5087062 0.75 TNFRSF1A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1785429-B1 PROCESS FOR PRODUCING METALLOCENE COMPOUND SUMITOMO CHEMICAL CO (JP) 2012-10-03 EP disclosed
US-7652159-B2 Process for producing metallocene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-26 US disclosed
US-20080319213-A1 Process For Producing Metallocene Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-12-25 US disclosed
EP-1785429-A1 PROCESS FOR PRODUCING METALLOCENE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-16 EP disclosed