SCHEMBL3677660

SCHEMBL3677660

CCCOC(=O)/C=C\C(N)=O

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.67
ATM Q13315 1/20 0.59
MAPT P10636 3/20 0.53
RAB9A P51151 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
APP P05067 2/20 0.44
ALOX5 P09917 1/20 0.42
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
PKM P14618 1/20 0.40
HTT P42858 1/20 0.40
NLRP1 Q9C000 1/20 0.40
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448456 0.89 HCAR2 (0.82) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL322228 0.89 HCAR2 (0.82) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL448454 0.89 HCAR2 (0.82) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9330009 0.88 ATM (0.80) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL10916517 0.88 ATM (0.80) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL27876632 0.86 ATM (0.50) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL4934756 0.86 HCAR2 (0.78) HCAR2ATMMAPTRAB9ANPSR1
Hydrochloric Acid SCHEMBL28061109 0.86 HCAR2 (0.78) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL4334173 0.86 ATM (0.70) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9360643 0.84 HCAR2 (0.71) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115353644-A Spherical particles comprising carbon nanomaterial-graft-polyamide, method for the production thereof and use thereof 施乐公司 2022-11-18 CN disclosed
CN-115353745-A Spherical particles comprising a carbon nanomaterial graft polymer, method for the production thereof and use thereof 施乐公司 2022-11-18 CN disclosed
CN-114539765-A Compositions, methods, and articles relating to in situ crosslinking of polyamides during additive manufacturing 施乐公司 2022-05-27 CN disclosed
US-8597790-B2 Rubber compositions containing non-sulfur silica coupling agents bound to diene rubbers BRIDGESTONE CORPORATION (JP) 2013-12-03 US disclosed
US-20130274374-A1 RUBBER COMPOSITIONS CONTAINING NON-SULFUR SILICA COUPLING AGENTS BOUND TO DIENE RUBBERS BRIDGESTONE CORPORATION (JP) 2013-10-17 US disclosed
US-8329297-B2 Rubber compositions containing non-sulfur silica coupling agents bound to diene rubbers BRIDGESTONE CORPORATION (JP) 2012-12-11 US disclosed
US-20100132868-A1 RUBBER COMPOSITIONS CONTAINING NON-SULFUR SILICA COUPLING AGENTS BOUND TO DIENE RUBBERS BRIDGESTONE CORPORATION (JP) 2010-06-03 US disclosed
EP-1981823-A1 DISPERSION COMPRISING SILICON DIOXIDE AND POLYCARBOXYLATE ETHER Evonik Degussa GmbH (DE) 2008-10-22 EP disclosed
EP-1981824-A2 DISPERSION COMPRISING TITANIUM DIOXIDE AND POLYCARBOXYLATE ETHER Evonik Degussa GmbH (DE) 2008-10-22 EP disclosed
WO-2007088111-A1 DISPERSION COMPRISING SILICON DIOXIDE AND POLYCARBOXYLATE ETHER EVONIK DEGUSSA GMBH (DE) 2007-08-09 WO disclosed
WO-2007088110-A2 DISPERSION COMPRISING TITANIUM DIOXIDE AND POLYCARBOXYLATE ETHER EVONIK DEGUSSA GMBH (DE) 2007-08-09 WO disclosed
EP-0393713-B1 Process for the preparation of N-substituted maleimides TOSOH CORP (JP) 1994-06-29 EP disclosed
US-5087705-A Heating N-substituted maleamic acid monoester in presence of acid catalyst SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) 1992-02-11 US disclosed
EP-0393713-A1 Process for the preparation of N-substituted maleimides Tosoh Corporation (JP) 1990-10-24 EP disclosed