Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.78 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448456 | 0.97 | HCAR2 (0.82) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL448454 | 0.97 | HCAR2 (0.82) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL322228 | 0.97 | HCAR2 (0.82) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL28061109 | 0.95 | HCAR2 (0.78) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL5285060 | 0.90 | HCAR2 (0.72) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Diethyl Maleate SCHEMBL9642988 | 0.90 | HCAR2 (0.72) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL5287207 | 0.90 | HCAR2 (0.72) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Ethylene Glycol SCHEMBL28539292 | 0.90 | HCAR2 (0.72) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL5285059 | 0.90 | HCAR2 (0.72) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Propyl Fumarate SCHEMBL322230 | 0.88 | HCAR2 (1.00) | HCAR2ATMMAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004344-A1 | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use | ADITECH PHARMA AB (SE) | 2008-01-03 | — | — | US | claimed |
| EP-1812374-A1 | NOVEL SALTS OF FUMARIC ACID MONOALKYLESTERS AND THEIR PHARMACEUTICAL USE | Aditech Pharma AB (SE) | 2007-08-01 | — | — | EP | claimed |
| WO-2006050730-A1 | NOVEL SALTS OF FUMARIC ACID MONOALKYLESTERS AND THEIR PHARMACEUTICAL USE | ADITECH PHARMA AB (SE) | 2006-05-18 | — | — | WO | claimed |
| US-20080004344-A1 | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use | ADITECH PHARMA AB (SE) | 2008-01-03 | — | — | US | disclosed |
| EP-1812374-A1 | NOVEL SALTS OF FUMARIC ACID MONOALKYLESTERS AND THEIR PHARMACEUTICAL USE | Aditech Pharma AB (SE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006050730-A1 | NOVEL SALTS OF FUMARIC ACID MONOALKYLESTERS AND THEIR PHARMACEUTICAL USE | ADITECH PHARMA AB (SE) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004344-A1 | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use | FAH, FH, SLC16A7 | HCAR2 33/4885ATM 4178/4885MAPT 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.