SCHEMBL3677784

SCHEMBL3677784

Cc1cc(C(c2cc(C)c(OCC3CO3)c(C)c2)c2cc(C)c(OCC3CO3)c(C)c2)cc(C)c1OCC1CO1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
GLA P06280 1/20 0.46
TSHR P16473 5/20 0.44
TP53 P04637 3/20 0.44
HIF1A Q16665 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CYP3A4 P08684 1/20 0.44
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP1A2 P05177 1/20 0.40
PPARG P37231 1/20 0.40
PKM P14618 2/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
MAPK1 P28482 1/20 0.32
VDR P11473 1/20 0.32
FGFR1 P11362 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21775754 0.91 ALDH1A1 (0.43) ALDH1A1GLATSHRTP53HIF1A
SCHEMBL9738048 0.89 ALDH1A1 (0.46) ALDH1A1GLATSHRTP53HIF1A
SCHEMBL23627375 0.88 ALDH1A1 (0.41) ALDH1A1GLATSHRTP53HIF1A
SCHEMBL10695385 0.86 ALDH1A1 (0.40) ALDH1A1GLATSHRTP53HIF1A
SCHEMBL26299286 0.84 ALDH1A1 (0.47) ALDH1A1GLATSHRTP53HIF1A
SCHEMBL10430018 0.83 ALDH1A1 (0.41) ALDH1A1GLATSHRTP53HIF1A
SCHEMBL49658 0.83 ALDH1A1 (0.50) ALDH1A1GLATSHRTP53HIF1A
SCHEMBL4470150 0.83 ALDH1A1 (0.50) ALDH1A1GLATSHRTP53HIF1A
SCHEMBL13117147 0.83 ALDH1A1 (0.50) ALDH1A1GLATSHRTP53HIF1A
SCHEMBL30353125 0.82 ALDH1A1 (0.41) ALDH1A1GLATSHRTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7049388-B2 Process for manufacturing an α-dihydroxy derivative and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2006-05-23 US claimed
US-6646102-B2 Epoxidizing an alpha - halohydrin intermediate produced from a halide substitution of an alpha -dihydroxy derivative which has been obtained by a dihydroxylation reaction of an aryl allyl ether, oxidation catalysts DOW GLOBAL TECHNOLOGIES INC. 2003-11-11 US claimed
US-20030105268-A1 Process for manufacturing an alpha-dihydroxy derivative and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. 2003-06-05 US claimed
US-7807012-B2 Moldable compositions containing carbinol functional silicone resins or anhydride functional silicone resins DOW CORNING CORPORATION (US) 2010-10-05 US disclosed
EP-1809701-B1 MOLDABLE COMPOSITIONS CONTAINING CARBINOL FUNCTIONAL SILICONE REISINS OR ANHYDRIDE FUNCTIONAL SILICONE RESINS DOW CORNING (US) 2009-08-05 EP disclosed
US-20080105375-A1 Moldable Compositions Containing Carbinol Functional Silicone Resins or Anhydride Functional Silicone Resins DOW CORNING CORPORATION (US) 2008-05-08 US disclosed
US-7049388-B2 Process for manufacturing an α-dihydroxy derivative and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2006-05-23 US disclosed
US-20060074149-A1 Process for manufacturing an alpha-dihydroxy derivative and epoxy resins prepared therefrom BORIACK CLINTON J 2006-04-06 US disclosed
EP-1406885-B1 PROCESS FOR MANUFACTURING AN A-DIHYDROXY DERIVATIVE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC (US) 2006-01-18 EP disclosed
US-20040049004-A1 Process for manufacturing an alpha-dihydroxy derivative and epoxy resins prepared therefrom THE DOW CHEMICAL COMPANY 2004-03-11 US disclosed
US-6646102-B2 Epoxidizing an alpha - halohydrin intermediate produced from a halide substitution of an alpha -dihydroxy derivative which has been obtained by a dihydroxylation reaction of an aryl allyl ether, oxidation catalysts DOW GLOBAL TECHNOLOGIES INC. 2003-11-11 US disclosed
US-20030105268-A1 Process for manufacturing an alpha-dihydroxy derivative and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. 2003-06-05 US disclosed
EP-0251431-A2 Epoxy resin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-01-07 EP disclosed