SCHEMBL3677977

SCHEMBL3677977

Oc1cccc(SSSSc2ccccc2)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.41
HSD17B10 Q99714 6/20 0.41
ALOX15 P16050 5/20 0.41
ALDH1A1 P00352 5/20 0.41
MAPT P10636 4/20 0.41
LMNA P02545 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
CA2 P00918 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
EGFR P00533 2/20 0.41
FYN P06241 2/20 0.41
MMP9 P14780 2/20 0.41
RECQL P46063 2/20 0.41
MMP2 P08253 2/20 0.41
CA1 P00915 2/20 0.41
MGLL Q99685 1/20 0.41
ADAMTS4 O75173 1/20 0.41
MMP8 P22894 1/20 0.41
CA6 P23280 1/20 0.41
CDK2 P24941 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3684644 0.88 HPGD (0.50) HPGDHSD17B10ALOX15ALDH1A1MAPT
SCHEMBL6704941 0.79 ALDH1A1 (0.58) HPGDHSD17B10ALOX15ALDH1A1MAPT
SCHEMBL595125 0.78 ALDH1A1 (0.46) HPGDHSD17B10ALOX15ALDH1A1MAPT
SCHEMBL9160401 0.74 ALDH1A1 (0.47) HPGDHSD17B10ALOX15ALDH1A1MAPT
SCHEMBL1253222 0.73 HPGD (0.73) HPGDHSD17B10ALDH1A1MAPTLMNA
SCHEMBL7635557 0.73 HPGD (0.57) HPGDHSD17B10ALOX15ALDH1A1MAPT
SCHEMBL10983769 0.72 ALDH1A1 (0.45) HPGDHSD17B10ALOX15ALDH1A1MAPT
SCHEMBL11419491 0.71 ALDH1A1 (0.48) HPGDHSD17B10ALOX15ALDH1A1MAPT
SCHEMBL11325155 0.71 HPGD (0.69) HPGDHSD17B10ALDH1A1MAPTLMNA
SCHEMBL11313468 0.71 HPGD (0.69) HPGDHSD17B10ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3211017-A1 POLYURETHANE Compagnie Générale des Etablissements Michelin (FR) 2017-08-30 EP disclosed
EP-2115033-B1 POLYURETHANE MICHELIN & CIE (FR) 2017-05-17 EP disclosed
US-20130287982-A1 POLYURETHANE MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-10-31 US disclosed
US-8512834-B2 Polyurethane COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2013-08-20 US disclosed
US-20100047493-A1 Polyurethane COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2010-02-25 US disclosed
EP-2115033-A1 POLYURETHANE Societe de Technologie Michelin (FR) 2009-11-11 EP disclosed
WO-2008077151-A1 POLYURETHANE SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-06-26 WO disclosed