⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26967671 | 0.79 | — | — | |
| SCHEMBL1337861 | 0.79 | — | — | |
| SCHEMBL3110038 | 0.75 | — | — | |
| SCHEMBL2485973 | 0.75 | — | — | |
| SCHEMBL30911158 | 0.75 | — | — | |
| SCHEMBL23500908 | 0.75 | — | — | |
| SCHEMBL2848313 | 0.75 | — | — | |
| SCHEMBL1967648 | 0.75 | — | — | |
| SCHEMBL22660171 | 0.75 | — | — | |
| SCHEMBL1290015 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395311-B | Intermediates and processes for preparing compounds | 基因泰克公司 | 2017-04-19 | — | — | CN | claimed |
| CN-104395311-A | Intermediates and processes for preparing compounds | GENENTECH INC | 2015-03-04 | — | — | CN | claimed |
| CN-105658638-B | compounds with insecticidal activity | 拜耳作物科学股份公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-104395311-B | Intermediates and processes for preparing compounds | 基因泰克公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-104395311-A | Intermediates and processes for preparing compounds | GENENTECH INC | 2015-03-04 | — | — | CN | disclosed |
| US-7745646-B2 | Bicyclic heteroaryl inhibitors of PDE4 | KALYPSYS, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-20080027112-A1 | BICYCLIC HETEROARYL INHIBITORS OF PDE4 | Govek, Steven (US) | 2008-01-31 | — | — | US | disclosed |
| WO-2008006051-A2 | BICYCLIC HETEROARYL INHIBITORS OF PDE4 | GOVEK STEVEN P (US) | 2008-01-10 | — | — | WO | disclosed |