SCHEMBL3678396

SCHEMBL3678396

CC(C)(N)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.66
TSHR P16473 3/20 0.66
MAPK1 P28482 3/20 0.66
MEN1 O00255 3/20 0.66
KMT2A Q03164 3/20 0.66
CYP1A2 P05177 2/20 0.66
CYP3A4 P08684 2/20 0.66
BLM P54132 2/20 0.66
ATM Q13315 2/20 0.66
HIF1A Q16665 2/20 0.66
NPSR1 Q6W5P4 2/20 0.66
LMNA P02545 2/20 0.66
ALOX15 P16050 2/20 0.66
GMNN O75496 1/20 0.66
GABBR2 O75899 1/20 0.66
TP53 P04637 1/20 0.66
CYP2C9 P11712 1/20 0.66
NFKB1 P19838 1/20 0.66
CYP2C19 P33261 1/20 0.66
PMP22 Q01453 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9544866 0.94 ALDH1A1 (0.59) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL9546317 0.85 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL3238817 0.84 ALDH1A1 (0.68) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL16772307 0.84 ALDH1A1 (0.68) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL11585986 0.84 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL22356835 0.83 ALDH1A1 (0.66) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL11254110 0.82 ALDH1A1 (0.70) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL11587517 0.82 ALDH1A1 (0.46) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL11776752 0.81 ALDH1A1 (0.63) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL11310908 0.81 ALDH1A1 (0.63) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1188778-A Silicone molding compositions having extended useful life GEN ELECTRIC (US) 1998-07-29 CN claimed
US-4097527-A REACTING A 3,5-DI-TERT-ALKYL-4-HYDROXYBENZYL HALIDE, N,N-DIALKYL AMINE OR DITHIOCARBAMATE AND A NITROPROPANE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-06-27 US claimed
US-7807757-B2 stabilizing and at the same time phase compatibilizing plastics or plastic compositions by incorporating maleic anhydride or acrylic acid grafted copolymer or terpolymer (styrene/butadiene/styrene block copolymer grafted with maleic anhydride) obtained by reacting with a benzotriazole compound CIBA SPECIALTY CHEMICALS CORP. (US) 2010-10-05 US disclosed
US-20080051521-A1 Functionalized polymers PFAENDNER RUDOLF 2008-02-28 US disclosed
US-7300978-B2 Functionalised polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-11-27 US disclosed
CN-100340597-C Silicone molding compositions having extended useful life GEN ELECTRIC (US) 2007-10-03 CN disclosed
CN-1289537-C Functionalized polymers CIBA SC HOLDING AG (CH) 2006-12-13 CN disclosed
US-6828364-B2 Two different sterically hindered amine compounds, and a salt of magnesium or zinc CIBA SPECIALTY CHEMICALS CORPORATION 2004-12-07 US disclosed
US-20040167291-A1 Functionalised polymers PFAENDNER RUDOLF (DE) 2004-08-26 US disclosed
US-20020123577-A1 Functionalised polymers PFAENDNER RUDOLF (DE) 2002-09-05 US disclosed
US-6362278-B1 STABILIZATION USING STERIC HINDERED AMINE COMPOUND CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-26 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
US-4246198-A STABILIZERS AGAINST OXIDATIVE DEGRADATION CIBA-GEIGY CORPORATION (US) 1981-01-20 US disclosed
US-4098760-A NON-MIGRATORY, NON-LEACHING UNIROYAL, INC. (US) 1978-07-04 US disclosed
US-4097527-A REACTING A 3,5-DI-TERT-ALKYL-4-HYDROXYBENZYL HALIDE, N,N-DIALKYL AMINE OR DITHIOCARBAMATE AND A NITROPROPANE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-06-27 US disclosed
US-4097527-A REACTING A 3,5-DI-TERT-ALKYL-4-HYDROXYBENZYL HALIDE, N,N-DIALKYL AMINE OR DITHIOCARBAMATE AND A NITROPROPANE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-06-27 US disclosed