SCHEMBL3678604

SCHEMBL3678604

CC(=O)c1cc(C)[nH]c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.47
GAA P10253 3/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
NOTUM Q6P988 1/20 0.38
KDM4E B2RXH2 5/20 0.36
HSD17B10 Q99714 3/20 0.36
HPGD P15428 1/20 0.36
MAPT P10636 4/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CA1 P00915 1/20 0.34
DAO P14920 1/20 0.34
HCAR2 Q8TDS4 1/20 0.34
GLA P06280 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL593547 0.81 NOTUM (0.57) BRD4GAANOTUMKDM4EHSD17B10
SCHEMBL1981368 0.79 BRD4 (0.55) BRD4GAANOTUMKDM4EHSD17B10
SCHEMBL4848024 0.79 NOTUM (0.37) BRD4GAANPC1POLBSMN1; SMN2
SCHEMBL14449924 0.79 SMN1; SMN2 (0.42) BRD4GAANPC1POLBSMN1; SMN2
SCHEMBL8095191 0.76 KDM4E (0.38) BRD4GAANPC1POLBNOTUM
SCHEMBL9477063 0.76 GAA (0.55) BRD4GAANPC1POLBSMN1; SMN2
SCHEMBL78402 0.76 MAPT (0.55) GAANPC1POLBKDM4EHSD17B10
SCHEMBL17268384 0.73 CDC7 (0.37) BRD4GAANPC1POLBSMN1; SMN2
SCHEMBL9475977 0.73 KDM4E (0.67) BRD4GAANPC1POLBSMN1; SMN2
SCHEMBL21333130 0.73 NOTUM (0.33) BRD4GAANOTUMKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS CORN PRODUCTS DEV INC (US) 2026-02-05 US disclosed
EP-4561366-A1 FLAVOR MODIFYING COMPOSITION CORN Products Development Inc. (US) 2025-06-04 EP disclosed
CN-119894387-A Flavor modulating composition 玉米产品开发公司 2025-04-25 CN disclosed
US-20250081996-A1 FLAVOR MODIFYING COMPOSITION PURECIRCLE SDN BHD (MY) 2025-03-13 US disclosed
EP-4380375-A1 METHODS FOR THERMALLY INHIBITING STARCH CORN Products Development Inc. (US) 2024-06-12 EP disclosed
CN-117835831-A Flavor modulating composition 玉米产品开发公司 2024-04-05 CN disclosed
WO-2024026450-A1 FLAVOR MODIFYING COMPOSITION CORN PRODUCTS DEVELOPMENT, INC. (US) 2024-02-01 WO disclosed
WO-2023014926-A1 FLAVOR MODIFYING COMPOSITION CORN PRODUCTS DEVELOPMENT, INC. (US) 2023-02-09 WO disclosed
EP-3554275-A1 MODIFYING OR ENHANCING A FLAVOR OF FOOD AND BEVERAGE PRODUCTS Tate & Lyle Ingredients Americas LLC (US) 2019-10-23 EP disclosed
US-20190313680-A1 MODIFYING OR ENHANCING A FLAVOR OF FOOD AND BEVERAGE PRODUCTS TATE & LYLE INGREDIENTS AMERICAS LLC (US) 2019-10-17 US disclosed
US-20070185364-A1 In-line process for generating comonomer EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-09 US disclosed
US-20070185358-A1 Process for generating linear alpha olefin comonomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-09 US disclosed
US-4303689-A Flavoring with pyrazine derivatives FIRMENICH SA (CH) 1981-12-01 US disclosed
US-4138410-A Flavoring agent FIRMENICH & CIE (CH) 1979-02-06 US disclosed
US-4085109-A Pyridine sulfur flavoring agents FIRMENICH & CIE (CH) 1978-04-18 US disclosed
US-3989713-A Pyrrylmethylthio flavoring agents FIRMENICH & CIE (CH) 1976-11-02 US disclosed
US-3952026-A FLAVOR ADDITIVE FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1976-04-20 US disclosed
US-3952024-A FLAVOR ADDITIVE FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1976-04-20 US disclosed
US-3931245-A FURYLALKYLTHIOL CARBOXYLATES FIRMENICH & CIE (CH) 1976-01-06 US disclosed
US-3931246-A FURYLALKYL-THIOETHERS FIRMENICH & CIE (CH) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS TAS2R42, TAS2R7, TAS2R31 BRD4 2430/4885GAA 336/4885NPC1 2867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.