TAS2R42

Taste receptor type 2 member 42 · Q7RTR8 · TAS2R42 on Sugi Atlas →

479 patent compounds predicted against TAS2R42, 408 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Isoproterenol (SCHEMBL4165)	1.00	1/20
Isoproterenol (SCHEMBL4166)	1.00	1/20
Levisoprenaline (SCHEMBL250806)	1.00	1/20
Isoproterenol (SCHEMBL3253794)	1.00	1/20
Isoproterenol (SCHEMBL29386243)	1.00	1/20
Isoproterenol (SCHEMBL29519146)	1.00	1/20
Levisoprenaline (SCHEMBL29620666)	1.00	1/20
Isoproterenol (SCHEMBL7627)	0.97	1/20
Isoproterenol (SCHEMBL1333049)	0.97	1/20
Isoproterenol (SCHEMBL3672791)	0.97	1/20
Levisoprenaline (SCHEMBL4745572)	0.97	1/20
Isoproterenol (SCHEMBL5682030)	0.97	1/20
Isoproterenol (SCHEMBL6151626)	0.97	1/20
Isoproterenol (SCHEMBL9614622)	0.97	1/20
Isoproterenol (SCHEMBL28872988)	0.97	1/20
Isoproterenol (SCHEMBL3669257)	0.93	1/20
Isoproterenol (SCHEMBL28121226)	0.90	1/20
Isoproterenol (SCHEMBL2232971)	0.88	1/20
Isoproterenol (SCHEMBL28106224)	0.88	1/20
Isoproterenol (SCHEMBL28296538)	0.88	1/20

Clinical trials — most relevant to TAS2R42 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Trial of Efficacy and Safety of Raphamin in the Treatment of Coronavirus Disease 2019 in Outpatients	PHASE3	COMPLETED
Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes	PHASE2	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Satiation Peptides	PHASE1	COMPLETED
Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults	nan	COMPLETED
Gustin Gene Polymorphism and 6-n-propylthiouracil (PROP) Taste	nan	COMPLETED
TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries	nan	COMPLETED
Allele-specific Expression of a Bitter Taste Receptor	nan	COMPLETED
Fructose and Glucose and TAS1R2 in Type 1 Diabetes	nan	COMPLETED
Flavour Programming: Fruit and Vegetable Palatability	nan	COMPLETED
Ibuprofen Inhibits Human Sweet Taste	nan	COMPLETED
Astringency and Oral Health	nan	COMPLETED
Sensory Study: Taste and Tongue Biology	nan	COMPLETED
NUTRACORE, Glycaemic Index and Appetite	nan	COMPLETED
Bitter Taste Receptors in Oropharynx Cancer	nan	UNKNOWN
Taste Perception and Chronic Disease Risk	nan	COMPLETED
Factors Affecting Salt Intake in Young Adults	nan	UNKNOWN
Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults	nan	COMPLETED
A Study of the Function of Hormones Present In Taste Buds	nan	COMPLETED
Study of Taste Deficits	nan	COMPLETED
Sucralose and Lactisole Additions to OGTT in Humans	nan	COMPLETED
Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)	nan	RECRUITING
The Effect of Lactisole on the Responses to Glucose Solution	nan	UNKNOWN
Genetic Variability in Taste Perception	nan	COMPLETED
The Effect of Artificial Sweeteners on Blood Glucose Response	nan	WITHDRAWN
The Obese Taste Bud Study	nan	UNKNOWN
Gustatory Dysfunction Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy	nan	COMPLETED
CD36 and Human Fat Taste Perception	nan	COMPLETED
Impacts of Sugar-Sweetened Beverage on Body Weight	nan	COMPLETED
Novel Role of Exercise Timing in Obesity	nan	COMPLETED
The Effects of GLP-1 Receptor Agonists on Chemosensory Function and Ingestive Behavior	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a TAS2R42 binder may also engage these)

Protein	Name	Similarity
Q645U9	—	1.000	Q645U9 →
Q5Y4Z2	—	1.000	Q5Y4Z2 →
Q645T9	—	1.000	Q645T9 →
Q645Z3	—	1.000	Q645Z3 →
Q646B8	—	1.000	Q646B8 →
Q646G3	—	1.000	Q646G3 →
Q646G5	—	0.999	Q646G5 →
Q7M722	—	0.999	Q7M722 →
TAS2R3	Taste receptor type 2 member 3	0.998	landscape →
Q7M707	—	0.998	Q7M707 →
Q7TQA8	—	0.998	Q7TQA8 →
Q9JKT5	—	0.997	Q9JKT5 →
Q646C6	—	0.997	Q646C6 →
Q646E8	—	0.996	Q646E8 →
Q7M709	—	0.996	Q7M709 →
Q675B9	—	0.996	Q675B9 →
TAS2R9	Taste receptor type 2 member 9	0.996	landscape →
Q9JKT8	—	0.996	Q9JKT8 →
P59528	—	0.996	P59528 →
Q7M723	—	0.996	Q7M723 →
Q645U2	—	0.996	Q645U2 →
Q67ES6	—	0.995	Q67ES6 →
Q7M717	—	0.994	Q7M717 →
Q67ET7	—	0.994	Q67ET7 →
Q675C0	—	0.994	Q675C0 →
Q646A7	—	0.994	Q646A7 →
Q645T0	—	0.994	Q645T0 →
Q67ES5	—	0.993	Q67ES5 →
Q9JKT9	—	0.993	Q9JKT9 →
TAS2R13	Taste receptor type 2 member 13	0.993	landscape →