Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 10/20 | 0.59 |
| ▸ | P2RY4 | P51582 | 6/20 | 0.59 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.59 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687553 | 0.90 | POLB (0.62) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL3681643 | 0.90 | POLB (0.62) | POLGPOLBP2RY2P2RY4P2RY6 | |
| Deoxycytidine Triphosphate SCHEMBL29725285 | 0.89 | POLB (0.78) | POLGPOLBP2RY2P2RY4P2RY6 | |
| Deoxycytidine Triphosphate SCHEMBL12729518 | 0.89 | POLB (0.78) | POLGPOLBP2RY2P2RY4P2RY6 | |
| Deoxycytidine Triphosphate SCHEMBL12595481 | 0.89 | POLB (0.78) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL23414482 | 0.89 | POLG (0.69) | POLGPOLBP2RY2P2RY4P2RY6 | |
| Deoxycytidine Triphosphate SCHEMBL703664 | 0.89 | POLB (0.78) | POLGPOLBP2RY2P2RY4P2RY6 | |
| Deoxycytidine Triphosphate SCHEMBL18785037 | 0.89 | POLB (0.78) | POLGPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL29030090 | 0.89 | POLB (0.78) | POLGPOLBP2RY2P2RY4P2RY6 | |
| Deoxycytidine Triphosphate SCHEMBL42135 | 0.89 | POLB (0.78) | POLGPOLBP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829548-B2 | Compounds useful in the treatment of HIV | MEDIVIR AB (SE) | 2010-11-09 | — | — | US | disclosed |
| EP-1835916-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF HIV | MEDIVIR AB (SE) | 2009-04-01 | — | — | EP | disclosed |