Deoxycytidine Triphosphate

Deoxycytidine Triphosphate

SCHEMBL12595481

Nc1ccn([C@H]2C[C@@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)n1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.78
P2RY2 P41231 11/20 0.73
P2RY4 P51582 7/20 0.73
P2RY6 Q15077 6/20 0.73
POLG P54098 2/20 0.69
DUT P33316 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxycytidine Triphosphate SCHEMBL27673667 1.00 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG
Deoxycytidine Triphosphate SCHEMBL12729518 1.00 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG
Deoxycytidine Triphosphate SCHEMBL29725285 1.00 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG
Deoxycytidine Triphosphate SCHEMBL28008985 1.00 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG
Deoxycytidine Triphosphate SCHEMBL42135 1.00 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL29030090 1.00 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL1615548 1.00 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG
Deoxycytidine Triphosphate SCHEMBL18785037 1.00 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG
Deoxycytidine Triphosphate SCHEMBL703664 1.00 POLB (0.78) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL28420890 0.99 POLB (0.76) POLBP2RY2P2RY4P2RY6POLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170112948-A1 Inorganic-organic hybrid compound Karlsruher Institut für Technologie (DE) 2017-04-27 US disclosed
US-20170112948-A1 Inorganic-organic hybrid compound Karlsruher Institut für Technologie (DE) 2017-04-27 US disclosed
US-20150071921-A1 LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES EAGLE BIOLOGICS, INC. 2015-03-12 US disclosed
WO-2014093924-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2014-06-19 WO disclosed
US-20110118454-A1 METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150071921-A1 LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES IGFBP1, IGFBP5, IGF2BP1 POLB 3895/4885P2RY2 2768/4885P2RY4 2341/4885
US-20170112948-A1 Inorganic-organic hybrid compound SLCO4C1, SLCO2A1, SLCO1A2 POLB 3337/4885P2RY2 1037/4885P2RY4 518/4885
US-20110118454-A1 METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED PNP, NUDT1, DUT POLB 209/4885P2RY2 580/4885P2RY4 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.