SCHEMBL367880

SCHEMBL367880

Nc1ccc(C(=O)O)c(Cc2cc(N)ccc2C(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.59
ALDH1A1 P00352 7/20 0.59
MAPT P10636 5/20 0.59
CYP3A4 P08684 3/20 0.59
PTPN1 P18031 2/20 0.59
GAA P10253 2/20 0.59
ESR2 Q92731 1/20 0.59
TDP1 Q9NUW8 5/20 0.53
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
HPGD P15428 3/20 0.53
HSD17B10 Q99714 3/20 0.53
THRB P10828 2/20 0.53
RECQL P46063 2/20 0.53
POLB P06746 2/20 0.53
MCL1 Q07820 2/20 0.53
KDR P35968 2/20 0.53
USP2 O75604 1/20 0.53
PKM P14618 1/20 0.53
APEX1 P27695 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28062236 0.88 ALDH1A1 (0.59) KDM4EALDH1A1MAPTCYP3A4PTPN1
SCHEMBL2146135 0.87 PTPN1 (0.53) KDM4EALDH1A1MAPTCYP3A4PTPN1
SCHEMBL182142 0.86 ALDH1A1 (0.57) KDM4EALDH1A1MAPTCYP3A4PTPN1
SCHEMBL8768830 0.86 KDM4E (0.57) KDM4EALDH1A1MAPTCYP3A4PTPN1
SCHEMBL5374527 0.84 ALDH1A1 (0.55) KDM4EALDH1A1MAPTCYP3A4PTPN1
SCHEMBL343331 0.84 ALDH1A1 (0.55) KDM4EALDH1A1MAPTCYP3A4PTPN1
SCHEMBL29632107 0.84 ALDH1A1 (0.55) KDM4EALDH1A1MAPTCYP3A4PTPN1
SCHEMBL29632227 0.84 ALDH1A1 (0.55) KDM4EALDH1A1MAPTCYP3A4PTPN1
SCHEMBL21352086 0.84 KDM4E (0.55) KDM4EALDH1A1MAPTCYP3A4PTPN1
SCHEMBL308882 0.84 ALDH1A1 (0.55) KDM4EALDH1A1MAPTCYP3A4PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524852-B2 Thermoset polyurethanes based on moisture-resistance polyols for use in golf balls ACUSHNET COMPANY (US) 2013-09-03 US claimed
US-8288478-B2 Golf balls based on thermoplastic polyurethanes comprising moisture-resistant polyols ACUSHNET COMPANY (US) 2012-10-16 US claimed
US-20110256961-A1 THERMOSET POLYURETHANES BASED ON MOISTURE-RESISTANCE POLYOLS FOR USE IN GOLF BALLS JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2011-10-20 US claimed
US-20110207556-A1 GOLF BALLS BASED ON THERMOPLASTIC POLYURETHANES COMPRISING MOISTURE-RESISTANT POLYOLS JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2011-08-25 US claimed
US-7115703-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2006-10-03 US claimed
US-6903178-B2 Acid-functional polyurethane and polyurea compositions for golf balls ACUSHNET COMPANY (US) 2005-06-07 US claimed
US-20040220376-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US claimed
US-20040014535-A1 Acid-functional polyurethane and polyurea compositions for golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-01-22 US claimed
US-6610812-B1 Acid functional group based on a carboxylic, sulfonic or phosphonic acid ACUSHNET COMPANY 2003-08-26 US claimed
US-20030153716-A1 GOLF BALL COMPOSITIONS COMPRISING A NOVEL ACID FUNCTIONAL POLYURETHANE, POLYUREA, OR COPOLYMER THEREOF JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-08-14 US claimed
EP-0630666-B1 Polyurea covered golf ball ACUSHNET CO (US) 1998-11-11 EP claimed
US-5484870-A CLICK, FEEL; SHEAR AND CUT RESISTANCE; DURABILITY ACUSHNET COMPANY (US) 1996-01-16 US claimed
EP-0630666-A2 Polyurea covered golf ball ACUSHNET COMPANY (US) 1994-12-28 EP claimed
JP-7145222-A None JP disclosed
US-11834548-B2 Method of making golf ball incorporating improved polyurethane materials and resulting golf ball ACUSHNET COMPANY (US) 2023-12-05 US disclosed
CN-113680029-B Method of manufacturing a golf ball and resulting golf ball 高仕利公司 2023-02-24 CN disclosed
EP-0630666-B1 Polyurea covered golf ball ACUSHNET CO (US) 1998-11-11 EP disclosed
US-5484870-A CLICK, FEEL; SHEAR AND CUT RESISTANCE; DURABILITY ACUSHNET COMPANY (US) 1996-01-16 US disclosed
JP-H07145222-A POLYUREA COMPOSITION AND GOLF BALL MADE BY USING IT ACUSHNET CO 1995-06-06 JP disclosed
EP-0630666-A2 Polyurea covered golf ball ACUSHNET COMPANY (US) 1994-12-28 EP disclosed