SCHEMBL3678814

SCHEMBL3678814

CC(=O)C(C(=O)O)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.73
CYP2D6 P10635 1/20 0.52
LMNA P02545 3/20 0.50
MAPK1 P28482 1/20 0.50
HPGD P15428 1/20 0.45
KMT2A Q03164 1/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
PTGS2 P35354 1/20 0.42
MMP8 P22894 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7303581 1.00 SRC (0.73) SRCCYP2D6LMNAMAPK1HPGD
SCHEMBL1312762 0.90 SRC (0.64) SRCCYP2D6LMNAMAPK1HPGD
SCHEMBL15455826 0.88 SRC (0.61) SRCCYP2D6LMNAMAPK1HPGD
SCHEMBL11012611 0.88 SRC (0.61) SRCCYP2D6LMNAMAPK1HPGD
SCHEMBL6187748 0.87 PTGS2 (0.60) SRCPTGS2
SCHEMBL70165 0.85 SRC (1.00) SRCCYP2D6LMNAMAPK1KMT2A
SCHEMBL148725 0.85 SRC (1.00) SRCCYP2D6LMNAMAPK1KMT2A
SCHEMBL9374736 0.84 SRC (0.56) SRCCYP2D6LMNAMAPK1HPGD
Chloromethane SCHEMBL11628108 0.83 SRC (0.85) SRCCYP2D6LMNAMAPK1HPGD
Hydrochloric Acid SCHEMBL11211258 0.82 SRC (0.94) SRCCYP2D6LMNAMAPK1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217983-B Synthetic method of POSS nanoparticle reinforced quaternary ammonium salt antibacterial and anti-fouling silicone rubber 浙江工业大学 2025-05-02 CN claimed
CN-119505177-A Cured product of phosphonium styryl modified unsaturated resin and preparation method thereof 浙江工业大学 2025-02-25 CN claimed
CN-118422507-A Synthesis method for constructing antibacterial coating with polyboronic acid groups on substrate surface 浙江工业大学 2024-08-02 CN claimed
CN-117384026-A Preparation method of phenylacetic acid compound 台州臻挚生物科技有限公司 2024-01-12 CN claimed
CN-116217983-A Synthetic method of POSS nanoparticle reinforced quaternary ammonium salt antibacterial and anti-fouling silicone rubber 浙江工业大学 2023-06-06 CN claimed
CN-112341332-B Recycling method of sitagliptin key intermediate degradation waste 浙江昌明药业有限公司 2023-04-28 CN claimed
CN-108373814-A The polyurethane paint of strong adhesive force 浙江银鹿新材料有限公司 2018-08-07 CN claimed
EP-1462448-B1 Process for preparing substituted coumarins COUNCIL SCIENT IND RES (IN) 2006-05-10 EP claimed
WO-2000059616-A1 METHODS OF MAKING AND USING MICROCAPSULES WITH CONTROLLED DENSITY PETRAMEC, INC. (US) 2000-10-12 WO claimed
JP-1121298-A None JP disclosed
US-20250346610-A1 SUBSTITUTED PYRIDO[4,3-d]PYRIMIDINES AS KRAS MODULATORS ALTEROME THERAPEUTICS INC (US) 2025-11-13 US disclosed
US-12466842-B2 Substituted pyrido [4,3-d]pyrimidines as KRAS modulators ALTEROME THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
CN-116217983-B Synthetic method of POSS nanoparticle reinforced quaternary ammonium salt antibacterial and anti-fouling silicone rubber 浙江工业大学 2025-05-02 CN disclosed
CN-119170781-A Preparation method of sulfur-based composite material with self-repairing function layer coating 安徽通能新能源科技有限公司 2024-12-20 CN disclosed
US-4680338-A Bifunctional linker IMMUNOMEDICS, INC. (US) 1987-07-14 US disclosed
EP-0199087-A1 A liquid coating composition and a process for coating a substrate with such coating composition AKZO N.V. (NL) 1986-10-29 EP disclosed
US-4179511-A Antibacterial 3-(5-tetrazolyl) penam compounds PFIZER INC. (US) 1979-12-18 US disclosed
US-4143039-A ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS PFIZER INC. (US) 1979-03-06 US disclosed
US-4115385-A PENICILLINS PFIZER INC. (US) 1978-09-19 US disclosed
US-3933423-A Azoic dyeing of leather E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346610-A1 SUBSTITUTED PYRIDO[4,3-d]PYRIMIDINES AS KRAS MODULATORS KRAS, NRAS, HRAS SRC 790/4885CYP2D6 2098/4885LMNA 3394/4885
US-12466842-B2 Substituted pyrido [4,3-d]pyrimidines as KRAS modulators KRAS, NRAS, HRAS SRC 790/4885CYP2D6 2098/4885LMNA 3394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.