Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27661811 | 0.86 | CHRM3 (0.58) | CHRM3CHRM2CHRM1 | |
| SCHEMBL8663899 | 0.80 | CHRM3 (0.50) | CHRM3MLNRCHRM2CHRM1HTR2A | |
| SCHEMBL27681368 | 0.80 | CHRM3 (0.74) | CHRM3CHRM2CHRM1HRH1KCNH2 | |
| SCHEMBL9034523 | 0.79 | MAPT (0.57) | CYP19A1CHRM3MAPTKMT2ACHRM2 | |
| SCHEMBL27620093 | 0.78 | CHRM3 (0.56) | CYP19A1CHRM3CHRM2KCNH2 | |
| SCHEMBL31147060 | 0.78 | CYP19A1 (0.56) | CYP19A1CHRM3CHRM2KCNH2 | |
| SCHEMBL1610847 | 0.77 | CYP19A1 (0.55) | CYP19A1CHRM3CHRM2KCNH2 | |
| SCHEMBL17681414 | 0.77 | MAPT (0.59) | CHRM3MAPTKMT2ACHRM2CHRM1 | |
| SCHEMBL9334900 | 0.76 | CYP19A1 (1.00) | CYP19A1CHRM3MAPT | |
| SCHEMBL728471 | 0.75 | KCNN4 (0.67) | MAPTKMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261207-A1 | Intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives | Aventisub II Inc. (US) | 2010-12-15 | — | — | EP | claimed |