Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Atromepine SCHEMBL23494948 | 0.84 | HTR3A (0.56) | CHRM3CHRM2CHRM1HTR2CHRH1 | |
| Atromepine SCHEMBL247878 | 0.84 | HTR3A (0.56) | CHRM3CHRM2CHRM1HTR2CHRH1 | |
| Atromepine SCHEMBL247877 | 0.84 | HTR3A (0.56) | CHRM3CHRM2CHRM1HTR2CHRH1 | |
| Atromepine SCHEMBL23494947 | 0.84 | HTR3A (0.56) | CHRM3CHRM2CHRM1HTR2CHRH1 | |
| Atromepine SCHEMBL30869390 | 0.84 | HTR3A (0.56) | CHRM3CHRM2CHRM1HTR2CHRH1 | |
| SCHEMBL23494987 | 0.83 | CHRM1 (0.47) | CHRM3CHRM2CHRM1HTR2CHRH1 | |
| SCHEMBL23494986 | 0.83 | CHRM1 (0.47) | CHRM3CHRM2CHRM1HTR2CHRH1 | |
| Atromepine SCHEMBL22284034 | 0.83 | HTR3A (0.55) | CHRM3CHRM2CHRM1HTR2CHRH1 | |
| SCHEMBL23494989 | 0.83 | CHRM1 (0.47) | CHRM3CHRM2CHRM1HTR2CHRH1 | |
| SCHEMBL17880886 | 0.81 | CHRM1 (0.46) | CHRM3CHRM2CHRM1HTR2CHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833821-A1 | 1,3-OXAZIN-4-ONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000865-A1 | 1,3-OXAZIN-4-ONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-01-09 | — | — | WO | disclosed |