SCHEMBL3679130

SCHEMBL3679130

C/C(=C\CC(O)CCl)C(N)=O

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
ALDH1A1 P00352 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3679135 1.00 CA1 (0.30) CA1CA2ALDH1A1CA9
SCHEMBL1563831 0.82 ALDH1A1 (0.32) ALDH1A1
SCHEMBL596364 0.82 CD81 (0.33) CA1CA2ALDH1A1CA9
SCHEMBL445324 0.82 CD81 (0.33) CA1CA2ALDH1A1CA9
SCHEMBL547636 0.82 KDM4E (0.32)
SCHEMBL22207452 0.82 ALDH1A1 (0.32) ALDH1A1
SCHEMBL3232685 0.79 GRIK1 (0.41) ALDH1A1
SCHEMBL2047661 0.79 TDP1 (0.32)
SCHEMBL630861 0.79 GRIK1 (0.41) ALDH1A1
SCHEMBL548382 0.78 CHRM1 (0.31) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0213317-B1 BASE-CATALYZED, LOW TEMPERATURE SELF-CROSSLINKING POLYMERS National Starch and Chemical Investment Holding Corporation (US) 1991-12-04 EP claimed
US-20100094339-A1 COATING COMPOSITIONS COVIDIEN LP 2010-04-15 US disclosed
EP-2120824-A1 COATING COMPOSITIONS Tyco Healthcare Group LP (US) 2009-11-25 EP disclosed
WO-2008143654-A1 COATING COMPOSITIONS TYCO HEALTHCARE GROUP LP (US) 2008-11-27 WO disclosed
US-7160953-B2 Polymeric surface coatings BIOCOMPATIBLES UK LIMITED (GB) 2007-01-09 US disclosed
US-20040176556-A1 Polymeric surface coatings BIOCOMPATIBLES LIMITED 2004-09-09 US disclosed
US-6743878-B2 FOR IMPROVED BIOCOMPATIBILITY/HAEMOCOMPATIBILITY WITH LIVING TISSUES BIOCOMPATIBLES UK LIMITED (GB) 2004-06-01 US disclosed
US-20030190405-A1 Polymeric surface coatings BIOCOMPATIBLES LIMITED 2003-10-09 US disclosed
US-6395800-B1 BLEND OF 2-(METHACRYLOYLOXYETHYL)-2*-(TRIMETHYLAMMONIUM)ETHYL PHOSPHATE POLYMER; MEDICAL EQUIPMENT, CATHETERS; BIOCOMPATIBILITY BIOCOMPATIBLES LIMITED (GB) 2002-05-28 US disclosed
US-6284854-B1 NON-CROSSLINKED BIOCOMPATIBLE POLYMER IS FORMED FROM A RADICAL POLYMERISABLE ETHYLENICALLY UNSATURATED ZWITTERIONIC MONOMER CONTAINING A SULPHO-BETAINE ZWITTERIONIC GROUP BICCOMPATIBLES LIMITED (GB) 2001-09-04 US disclosed
US-5739236-A FOR ATTACHING LIGANDS TO POLYMER WHEN COATED ON A SURFACE BIOCOMPATIBLES LIMITED (GB) 1998-04-14 US disclosed
US-5712326-A TO IMPROVE BIOCOMPATIBILITY; REDUCE FIBRINOGEN ABSORPTION AND/OR PLATELET ACTIVATION BIOCOMPATIBLES LIMITED (GB) 1998-01-27 US disclosed
EP-0818479-A2 Polymeric surface coatings BIOCOMPATIBLES LIMITED (GB) 1998-01-14 EP disclosed
US-5705583-A RENDERING SURFACES BIOCOMPATIBLE BIOCOMPATIBLES LIMITED (GB) 1998-01-06 US disclosed
EP-0810239-A2 Polymeric surface coatings BIOCOMPATIBLES LIMITED (GB) 1997-12-03 EP disclosed
US-5648442-A ZWITTERIONIC POLYMERS BIOCOMPATIBLES LIMITED (GB) 1997-07-15 US disclosed
EP-0626983-A1 POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS BIOCOMPATIBLES LIMITED (GB) 1994-12-07 EP disclosed
WO-1994014897-A1 POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS BIOCOMPATIBLES LIMITED (GB) 1994-07-07 WO disclosed
EP-0593561-A1 POLYMERIC SURFACE COATINGS BIOCOMPATIBLES LIMITED (GB) 1994-04-27 EP disclosed
WO-1993001221-A1 POLYMERIC SURFACE COATINGS BIOCOMPATIBLES LIMITED (GB) 1993-01-21 WO disclosed