Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799262 | 0.76 | TSHR (0.41) | TSHRARKDM5AL3MBTL1KDM4E | |
| SCHEMBL23625536 | 0.75 | TSHR (0.52) | TSHRESR2ARL3MBTL1KDM4E | |
| SCHEMBL12251164 | 0.74 | TSHR (0.56) | TSHRARKDM5AL3MBTL1KDM4E | |
| SCHEMBL1472952 | 0.74 | TSHR (0.67) | TSHRESR2USP8USP7AR | |
| SCHEMBL222 | 0.73 | ESR2 (0.60) | TSHRESR2USP8USP7AR | |
| SCHEMBL29412287 | 0.73 | ESR2 (0.60) | TSHRESR2USP8USP7AR | |
| SCHEMBL21937408 | 0.71 | AR (0.40) | TSHRARKDM5AKDM4EALDH1A1 | |
| SCHEMBL8680517 | 0.71 | ESR2 (0.42) | TSHRESR2HPGDCYP1A2LMNA | |
| SCHEMBL29993589 | 0.70 | TSHR (0.50) | TSHRESR2USP8USP7AR | |
| SCHEMBL1133478 | 0.70 | TSHR (0.50) | TSHRESR2USP8USP7AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188232-A2 | METHOD FOR PRODUCING AROMATIC CARBONYL COMPOUNDS | Weylchem Frankfurt Gmbh (DE) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009033586-A2 | METHOD FOR PRODUCING AROMATIC CARBONYL COMPOUNDS | LEIBNIZ-INSTITUT FÜR KATALYSE E.V. AN DER UNIVERSITÄT ROSTOCK (DE) | 2009-03-19 | — | — | WO | disclosed |