Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12227223 | 0.91 | KDM4E (0.64) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL9625908 | 0.87 | KDM4E (0.69) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL2364940 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL11122118 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL11883345 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL9627195 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL9625872 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL9625662 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL9626411 | 0.85 | KDM4E (0.67) | KDM4EALDH1A1HTR1AADRA2CADRA2A | |
| SCHEMBL1506175 | 0.83 | MAPT (0.50) | KDM4EALDH1A1ADRB2ADRB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186013-A1 | Silicone/adhesive complex whereof the interface has a release force capable of being modulated by electron beam irradiation | RHODIA CHIMIE (FR) | 2003-10-02 | — | — | US | claimed |
| EP-0105341-B1 | VINYLOXY-FUNCTIONAL ORGANOPOLYSILOXANES COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1987-01-07 | — | — | EP | claimed |
| US-4617238-A | QUICK-CURING APCKAGING MATERIALS | GENERAL ELECTRIC COMPANY (US) | 1986-10-14 | — | — | US | claimed |
| EP-0105341-A4 | VINYLOXY-FUNCTIONAL ORGANOPOLYSILOXANES COMPOSITIONS. | GEN ELECTRIC (US) | 1984-09-13 | — | — | EP | claimed |
| EP-0105341-A1 | VINYLOXY-FUNCTIONAL ORGANOPOLYSILOXANES COMPOSITIONS. | GEN ELECTRIC (US) | 1984-04-18 | — | — | EP | claimed |
| WO-1983003418-A1 | VINYLOXY-FUNCTIONAL ORGANOPOLYSILOXANES COMPOSITIONS | GEN ELECTRIC (US) | 1983-10-13 | — | — | WO | claimed |
| CN-113366070-B | Method for preventing fogging during coating of flexible supports with crosslinkable liquid silicone compositions in a roll apparatus | 埃肯有机硅法国简易股份公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-113366070-A | Method for preventing fogging during coating of flexible supports with crosslinkable liquid silicone compositions in a roll apparatus | 埃肯有机硅法国简易股份公司 | 2021-09-07 | — | — | CN | disclosed |
| US-11078379-B2 | Method for the prevention of mist formation in a device comprising rolls during the coating of flexible media with a crosslinkable liquid silicone composition | ELKEM SILICONES FRANCE SAS (FR) | 2021-08-03 | — | — | US | disclosed |
| CN-109952352-B | Method for preventing fogging during coating of flexible supports with crosslinkable liquid silicone compositions in a roll apparatus | 埃肯有机硅法国简易股份公司 | 2021-04-20 | — | — | CN | disclosed |
| US-20190249036-A1 | METHOD FOR THE PREVENTION OF MIST FORMATION IN A DEVICE COMPRISING ROLLS DURING THE COATING OF FLEXIBLE MEDIA WITH A CROSSLINKABLE LIQUID SILICONE COMPOSITION | INSTITUT NATIONAL DES SCIENCES APPLIQUÉES (FR) | 2019-08-15 | — | — | US | disclosed |
| US-8519038-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2013-08-27 | — | — | US | disclosed |
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2012-08-30 | — | — | US | disclosed |
| US-6423378-B1 | IMPREGNATION ON SHEET GASKETS FOR ENGINES | RHODIA CHIMIE (FR) | 2002-07-23 | — | — | US | disclosed |
| US-5693688-A | AN ONIUM SALT | RHONE-POULENC CHIMIE (FR) | 1997-12-02 | — | — | US | disclosed |
| EP-0105341-B1 | VINYLOXY-FUNCTIONAL ORGANOPOLYSILOXANES COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1987-01-07 | — | — | EP | disclosed |
| US-4617238-A | QUICK-CURING APCKAGING MATERIALS | GENERAL ELECTRIC COMPANY (US) | 1986-10-14 | — | — | US | disclosed |
| EP-0105341-A4 | VINYLOXY-FUNCTIONAL ORGANOPOLYSILOXANES COMPOSITIONS. | GEN ELECTRIC (US) | 1984-09-13 | — | — | EP | disclosed |
| EP-0105341-A1 | VINYLOXY-FUNCTIONAL ORGANOPOLYSILOXANES COMPOSITIONS. | GEN ELECTRIC (US) | 1984-04-18 | — | — | EP | disclosed |
| WO-1983003418-A1 | VINYLOXY-FUNCTIONAL ORGANOPOLYSILOXANES COMPOSITIONS | GEN ELECTRIC (US) | 1983-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDOA, ALDH7A1, ALDH3A1 | KDM4E 1254/4885ALDH1A1 6/4885HTR1A 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.