Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676041 | 0.86 | HTR6 (0.46) | HTR6HTR2C | |
| SCHEMBL3338878 | 0.82 | HTR6 (0.49) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL3670408 | 0.81 | HTR6 (0.61) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL3670406 | 0.81 | HTR6 (0.61) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL13993619 | 0.81 | HTR6 (0.61) | HTR6HTR1ADRD2HTR2AHTR7 | |
| Formic Acid SCHEMBL3679749 | 0.81 | HTR6 (0.57) | HTR6HTR1ADRD2HTR2AHTR7 | |
| Formic Acid SCHEMBL3679742 | 0.81 | HTR6 (0.57) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL3624671 | 0.80 | HTR6 (0.45) | HTR6HTR2CHTR1ADRD2HTR2A | |
| SCHEMBL3625137 | 0.80 | HTR6 (0.45) | HTR6HTR2CHTR1ADRD2HTR2A | |
| SCHEMBL5097194 | 0.77 | HTR6 (0.49) | HTR6HTR1ADRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162433-A2 | 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | Memory Pharmaceuticals Corporation (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008147812-A2 | 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-12-04 | — | — | WO | disclosed |