Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | EEF2K | O00418 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3679938 | 1.00 | PRF1 (0.34) | PRF1MMP2MMP9MMP12EEF2K | |
| SCHEMBL13409940 | 0.94 | HPGD (0.35) | PRF1MMP2MMP9MMP12MMP8 | |
| SCHEMBL3679935 | 0.85 | PRF1 (0.33) | PRF1MMP2MMP9MAPTHPGD | |
| Trifluoroacetic Acid SCHEMBL3683119 | 0.85 | RXFP1 (0.46) | MMP8MMP13 | |
| Trifluoroacetic Acid SCHEMBL3683115 | 0.85 | RXFP1 (0.46) | MMP8MMP13 | |
| SCHEMBL14822900 | 0.83 | HPGD (0.39) | PRF1MMP2MMP9MMP12MAPT | |
| Trifluoroacetic Acid SCHEMBL3685117 | 0.79 | RAB9A (0.51) | MAPTGAAL3MBTL1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL3685112 | 0.79 | RAB9A (0.51) | MAPTGAAL3MBTL1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL3686963 | 0.79 | RXFP1 (0.47) | MMP8MMP13 | |
| Trifluoroacetic Acid SCHEMBL3689890 | 0.78 | EEF2K (0.35) | MMP2MMP9EEF2KMMP8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | PRF1 3750/4885MMP2 961/4885MMP9 1084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.