Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 12/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 12/20 | 1.00 |
| ▸ | CDK2 | P24941 | 12/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.65 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | CDK1 | P06493 | 5/20 | 0.63 |
| ▸ | FLT3 | P36888 | 2/20 | 0.61 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.59 |
| ▸ | PDE5A | O76074 | 1/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.59 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.59 |
| ▸ | CDK7 | P50613 | 1/20 | 0.59 |
| ▸ | CDK9 | P50750 | 1/20 | 0.59 |
| ▸ | CCNH | P51946 | 1/20 | 0.59 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5828199 | 0.88 | CDK2 (1.00) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL3681929 | 0.87 | CCNE2 (0.77) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL6143053 | 0.86 | CDK2 (1.00) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL3678763 | 0.81 | CCNE2 (1.00) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL28771433 | 0.78 | CDK2 (0.76) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL14071580 | 0.77 | CDK2 (0.85) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL3680752 | 0.76 | CCNE1 (0.82) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL1394958 | 0.74 | CCNE2 (1.00) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL2364042 | 0.73 | CDK1 (0.87) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL5827556 | 0.73 | CCNE2 (0.78) | CCNE2CCNE1CDK2CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764118-B1 | Polymer coating for medical devices | GILEAD PALO ALTO INC (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-1937328-B1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS INC (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7419709-B2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-20080160166-A1 | POLYMER COATING FOR MEDICAL DEVICES | RYPACEK FRANTISEK | 2008-07-03 | — | — | US | disclosed |
| US-7364768-B2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2008-04-29 | — | — | US | disclosed |
| US-20070071879-A1 | Polymer coating for medical devices | RYPACEK FRANTISEK | 2007-03-29 | — | — | US | disclosed |
| US-20070071926-A1 | Polymer coating for medical devices | RYPACEK FRANTISEK | 2007-03-29 | — | — | US | disclosed |
| EP-1764118-A2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2007-03-21 | — | — | EP | disclosed |
| US-7160592-B2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2007-01-09 | — | — | US | disclosed |
| US-20060093771-A1 | Polymer coating for medical devices | CV THERAPEUTICS, INC. | 2006-05-04 | — | — | US | disclosed |
| US-20030219562-A1 | Polymer coating for medical devices | CV THERAPEUTICS, INC. | 2003-11-27 | — | — | US | disclosed |