Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | UGT2B7 | P16662 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-Hydroxy-15,16-Bisnor-11-Labden-13-One SCHEMBL20640825 | 0.78 | PTPN2 (0.55) | PTPN1PTPN2EPAS1NFKB1NFKB2 | |
| SCHEMBL3681475 | 0.76 | PTPN2 (0.44) | PTPN1PTPN2UGT2B7 | |
| SCHEMBL20245300 | 0.74 | PTPN2 (0.48) | PTPN1PTPN2UGT2B7 | |
| SCHEMBL3678939 | 0.72 | PTPN2 (0.41) | PTPN1PTPN2EPAS1NFKB1NFKB2 | |
| SCHEMBL30200341 | 0.71 | PTPN2 (0.38) | PTPN1PTPN2NFKB1HIF1AUGT2B7 | |
| SCHEMBL14412297 | 0.70 | IDO1 (0.42) | PTPN1PTPN2EPAS1NFKB1NFKB2 | |
| SCHEMBL30706319 | 0.68 | PTPN2 (0.43) | PTPN1PTPN2UGT2B7 | |
| SCHEMBL8731624 | 0.66 | MAPT (0.40) | PTPN1PTPN2EPAS1IDO1HIF1A | |
| SCHEMBL24422153 | 0.64 | PTPN1 (1.00) | PTPN1PTPN2UGT2B7TRPA1CHRNB2 | |
| SCHEMBL18531567 | 0.62 | ALDH1A1 (0.32) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3335140-B1 | SYSTEMS, APPARATUS, AND METHODS FOR ANALYZING AND PREDICTING CELLULAR PATHWAYS | MASSACHUSETTS INST TECHNOLOGY (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20100112101-A1 | BIO-AVAILABILITY/BIO-EFFICACY ENHANCING ACTIVITY OF STEVIA REBAUDIANA AND EXTRACTS AND FRACTIONS AND COMPOUNDS THEREOF | LAILA IMPEX (IN) | 2010-05-06 | — | — | US | disclosed |