SCHEMBL3680409

SCHEMBL3680409

CCNCCC[Si](C)(OC)OCN

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.37
MEN1 O00255 1/20 0.37
GLA P06280 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 1/20 0.35
TSHR P16473 1/20 0.35
KDM1A O60341 5/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL550549 0.85 CYP2C19 (0.46) CYP2C19MEN1GLAKMT2ACYP1A2
Ammonia Solution, Strong SCHEMBL28253917 0.83 CYP2C19 (0.44) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL28098662 0.82 TSHR (0.40) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL10949415 0.81 CYP2C19 (0.48) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL28149490 0.81 CA12 (0.37) CYP2C19MEN1KMT2ACYP1A2TSHR
SCHEMBL2835148 0.80 CYP2C19 (0.38) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL15360652 0.79 CYP2C19 (0.48) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL27674343 0.79
SCHEMBL28874229 0.76 CA12 (0.35) CYP2C19MEN1KMT2ACYP1A2TSHR
SCHEMBL27864016 0.76 DNM1 (0.36) MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252866-B2 Azetidinium-functional polysaccharides and uses thereof GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-08-28 US claimed
US-9567655-B2 Processes for the separation of ores GEORGIA-PACIFIC CHEMICALS LLC (US) 2017-02-14 US disclosed
US-20140110621-A1 PROCESSES FOR THE SEPARATION OF ORES GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-04-24 US disclosed
US-8252866-B2 Azetidinium-functional polysaccharides and uses thereof GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-08-28 US disclosed
US-20100294725-A1 AZETIDINIUM-FUNCTIONAL POLYSACCHARIDES AND USES THEREOF GEORGIA-PACIFIC CHEMICALS LLC (US) 2010-11-25 US disclosed
WO-2009052362-A2 AZETIDINIUM-FUNCTIONAL POLYSACCHARIDES AND USES THEREOF GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-04-23 WO disclosed