Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 11/20 | 0.85 |
| ▸ | MAPT | P10636 | 3/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.85 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.85 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.85 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.85 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.85 |
| ▸ | GC | P02774 | 1/20 | 0.85 |
| ▸ | PGR | P06401 | 1/20 | 0.85 |
| ▸ | RXRA | P19793 | 1/20 | 0.85 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.85 |
| ▸ | CNR1 | P21554 | 1/20 | 0.85 |
| ▸ | HTR2C | P28335 | 1/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.85 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.85 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.85 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.85 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.85 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14005554 | 1.00 | VDR (0.85) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL16357615 | 1.00 | VDR (0.85) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL13875356 | 1.00 | VDR (0.85) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL3060963 | 1.00 | VDR (0.85) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL14489389 | 1.00 | VDR (0.85) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL14005545 | 1.00 | VDR (0.85) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL3219460 | 1.00 | VDR (0.85) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL14005553 | 1.00 | VDR (0.85) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL14029982 | 1.00 | VDR (0.85) | VDRMAPTADORA3SLC6A2AGTR1 | |
| SCHEMBL13392195 | 0.94 | VDR (0.77) | VDRMAPTADORA3SLC6A2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180064732-A1 | COMPOSITIONS AND METHODS FOR SUPPRESSING OR REDUCING SYSTEMIC IMMUNE RESPONSE IN A SUBJECT | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-08 | — | — | US | claimed |
| US-20100144683-A1 | METHODS FOR GENERATING MAMMALIAN MODELS OF ATOPIC DISEASES, AND SCREENING FOR THEIR TREATMENT | ASSOCIATION POUR LA RECHERCHE A L'IGBMC (ARI) (FR) | 2010-06-10 | — | — | US | claimed |
| US-11752159-B2 | Compositions and methods for suppressing or reducing systemic immune response in a subject | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2023-09-12 | — | — | US | disclosed |
| US-20210244748-A1 | COMPOSITIONS AND METHODS FOR SUPPRESSING OR REDUCING SYSTEMIC IMMUNE RESPONSE IN A SUBJECT | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2021-08-12 | — | — | US | disclosed |
| US-10980820-B2 | Compositions and methods for suppressing or reducing systemic immune response in a subject | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2021-04-20 | — | — | US | disclosed |
| US-20200101088-A1 | COMPOSITIONS AND METHODS FOR SUPPRESSING OR REDUCING SYSTEMIC IMMUNE RESPONSE IN A SUBJECT | UNIV PENNSYLVANIA (US) | 2020-04-02 | — | — | US | disclosed |
| US-10391107-B2 | Compositions and methods for suppressing or reducing systemic immune response in a subject | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180064732-A1 | COMPOSITIONS AND METHODS FOR SUPPRESSING OR REDUCING SYSTEMIC IMMUNE RESPONSE IN A SUBJECT | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-08 | — | — | US | disclosed |
| US-7820276-B2 | blend of biodegradable polyester ( polybutylene succinate terephthalate and polylactic acid) having different glass transition temperature; starch; and plasticizer( acetyl tributyl citrate); antifouling characteristic; a packaging material, an agricultural material | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20080044650-A1 | Matte Film or Sheet | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2008-02-21 | — | — | US | disclosed |