SCHEMBL368050

SCHEMBL368050

CCCCCOc1ccc2ccccc2n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 4/20 0.59
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
MAPT P10636 1/20 0.58
GPBAR1 Q8TDU6 4/20 0.57
CYSLTR1 Q9Y271 4/20 0.54
CYSLTR2 Q9NS75 3/20 0.54
MCHR1 Q99705 2/20 0.48
MAPK1 P28482 2/20 0.45
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
TSHR P16473 1/20 0.45
NFKB1 P19838 1/20 0.45
CYP2C19 P33261 1/20 0.45
HIF1A Q16665 1/20 0.45
GMNN O75496 1/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28276324 0.98 TLR8 (0.60) TLR8MEN1KMT2AMAPTGPBAR1
SCHEMBL16114537 0.98 TLR8 (0.60) TLR8MEN1KMT2AMAPTGPBAR1
SCHEMBL4273391 0.95 MAPT (0.59) TLR8MEN1KMT2AMAPTGPBAR1
SCHEMBL4269051 0.89 MEN1 (0.61) TLR8MEN1KMT2AMAPTGPBAR1
SCHEMBL30060467 0.89 MEN1 (0.61) TLR8MEN1KMT2AMAPTGPBAR1
SCHEMBL8067767 0.84 MEN1 (0.59) TLR8MEN1KMT2AMAPTGPBAR1
SCHEMBL30704390 0.84 MEN1 (0.59) TLR8MEN1KMT2AMAPTGPBAR1
SCHEMBL13196833 0.83 MAPT (0.55) TLR8MEN1KMT2AMAPTGPBAR1
SCHEMBL28900531 0.83 MEN1 (0.58) TLR8MEN1KMT2AMAPTGPBAR1
SCHEMBL5735971 0.82 MEN1 (0.61) TLR8MEN1KMT2AMAPTGPBAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112707887-A Preparation method of aryloxy quinoline compound 南昌弘益药业有限公司 2021-04-27 CN claimed
US-9184428-B2 Non-aqueous electrolytes for lithium ion batteries UCHICAGO ARGONNE LLC (US) 2015-11-10 US claimed
US-9012096-B2 Long life lithium batteries with stabilized electrodes UCHICAGO ARGONNE, LLC (US) 2015-04-21 US claimed
EP-2456793-A1 CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS Equistar Chemicals, LP (US) 2012-05-30 EP claimed
EP-2456795-A1 METHOD OF PREPARING NON-METALLOCENE CATALYSTS Equistar Chemicals, LP (US) 2012-05-30 EP claimed
US-8158733-B2 Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands EQUISTAR CHEMICALS, LP (US) 2012-04-17 US claimed
WO-2011011039-A1 METHOD OF PREPARING NON-METALLOCENE CATALYSTS EQUISTAR CHEMICALS, LP (US) 2011-01-27 WO claimed
US-20110021344-A1 Method for preparing non-metallocene ligands EQUISTAR CHEMICALS, LP 2011-01-27 US claimed
US-20110021727-A1 Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands EQUISTAR CHEMICALS, LP 2011-01-27 US claimed
WO-2011011040-A1 CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS EQUISTAR CHEMICALS, LP (US) 2011-01-27 WO claimed
US-7851092-B2 Redox shuttles for overcharge protection of lithium batteries U CHICAGO ARGONNE LLC (US) 2010-12-14 US claimed
WO-2006101779-A2 NON-AQUEOUS ELECTROLYTES FOR LITHIUM ION BATTERIES THE UNIVERSITY OF CHICAGO (US) 2006-09-28 WO claimed
US-20060210883-A1 Non-aqueous electrolytes for lithium ion batteries THE UNIVERSITY OF CHICAGO 2006-09-21 US claimed
WO-2006094069-A2 NOVEL REDOX SHUTTLES FOR OVERCHARGE PROTECTION OF LITHIUM BATTERIES UCHICAGO ARGONNE, LLC (US) 2006-09-08 WO claimed
US-20060199080-A1 Novel redox shuttles for overcharge protection of lithium batteries THE UNIVERSITY OF CHICAGO 2006-09-07 US claimed
US-20060147809-A1 Non-aqueous electrolyte of an alkali metal salt, a polar aprotic solvent, and an electrode stabilization additive comprising a linear, branched or cyclic hydrocarbon, other than a spirocyclic hydrocarbon, comprising at least one oxygen atom and at least one aryl, alkenyl or alkynyl group THE UNIVERSITY OF CHICAGO 2006-07-06 US claimed
US-12021226-B2 Cathode materials for secondary batteries UCHICAGO ARGONNE, LLC (US) 2024-06-25 US disclosed
CN-118047771-A Fungicidal oxadiazoles FMC公司 2024-05-17 CN disclosed
EP-0669321-A1 Use of 4-acyloxyquinoline derivatives as insecticides or acaricides and insecticidal or acaricidal compositions containing the same MEIJI SEIKA KABUSHIKI KAISHA (JP) 1995-08-30 EP disclosed
EP-0407192-A2 4-Acyloxyquinoline derivatives and insecticidal or acaricidal compositions containing same MEIJI SEIKA KABUSHIKI KAISHA (JP) 1991-01-09 EP disclosed