Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368050 | 0.95 | TLR8 (0.59) | MAPTMEN1KMT2ATLR8GPBAR1 | |
| SCHEMBL28276324 | 0.93 | TLR8 (0.60) | MAPTMEN1KMT2ATLR8GPBAR1 | |
| SCHEMBL16114537 | 0.93 | TLR8 (0.60) | MAPTMEN1KMT2ATLR8GPBAR1 | |
| SCHEMBL4269051 | 0.91 | MEN1 (0.61) | MAPTMEN1KMT2ATLR8GPBAR1 | |
| SCHEMBL30060467 | 0.91 | MEN1 (0.61) | MAPTMEN1KMT2ATLR8GPBAR1 | |
| SCHEMBL13196833 | 0.85 | MAPT (0.55) | MAPTMEN1KMT2ATLR8GPBAR1 | |
| SCHEMBL5735971 | 0.84 | MEN1 (0.61) | MAPTMEN1KMT2ATLR8GPBAR1 | |
| SCHEMBL9199234 | 0.84 | MEN1 (0.61) | MAPTMEN1KMT2ATLR8GPBAR1 | |
| SCHEMBL887723 | 0.83 | MAPT (0.56) | MAPTMEN1KMT2ATLR8CYSLTR1 | |
| SCHEMBL8067767 | 0.82 | MEN1 (0.59) | MAPTMEN1KMT2ATLR8GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981801-B | Production process for preparing cinchocaine hydrochloride by one-pot method | 山东诚汇双达药业有限公司 | 2023-02-24 | — | — | CN | claimed |
| CN-110606870-B | Polypeptide for preventing and treating eimeria tenella and pharmaceutical composition containing polypeptide | 广东省农业科学院动物卫生研究所 | 2021-02-19 | — | — | CN | claimed |
| CN-110606870-A | Polypeptide for preventing and treating eimeria tenella and pharmaceutical composition containing polypeptide | 广东省农业科学院动物卫生研究所 | 2019-12-24 | — | — | CN | claimed |
| CN-110312718-B | Heterocyclene derivatives as pest control agents | 拜耳公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-110981801-B | Production process for preparing cinchocaine hydrochloride by one-pot method | 山东诚汇双达药业有限公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-110981801-B | Production process for preparing cinchocaine hydrochloride by one-pot method | 山东诚汇双达药业有限公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-114302953-A | Bacillus strain and method for promoting plant growth | 奥本大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-113979941-A | Method for purifying naphthoquine ester | 瑞孚信江苏药业股份有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-110606870-B | Polypeptide for preventing and treating eimeria tenella and pharmaceutical composition containing polypeptide | 广东省农业科学院动物卫生研究所 | 2021-02-19 | — | — | CN | disclosed |
| CN-110606870-A | Polypeptide for preventing and treating eimeria tenella and pharmaceutical composition containing polypeptide | 广东省农业科学院动物卫生研究所 | 2019-12-24 | — | — | CN | disclosed |
| US-20190315710-A1 | Pd(II)-catalyzed Enantioselective Beta-Methylene C(sp3)–H Bond Activation | THE SCRIPPS RESEARCH INSTITUTE | 2019-10-17 | — | — | US | disclosed |
| CN-106306336-A | Mildew inhibitor for pet feed | 刘夕平 | 2017-01-11 | — | — | CN | disclosed |
| US-7605215-B2 | Process for producing olefin copolymerization catalyst and process for producing olefin copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20080227937-A1 | Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-09-18 | — | — | US | disclosed |
| WO-2005063777-A1 | BENZYLPHOSPHATE AND SUBSTITUTED BENZYLPHOSPHATE PRODRUGS FOR THE TREATMENT OF PULMONARY INFLAMMATION | CORUS PHARMA (US) | 2005-07-14 | — | — | WO | disclosed |
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0363212-B1 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5204348-A | Quinoline derivatives | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315710-A1 | Pd(II)-catalyzed Enantioselective Beta-Methylene C(sp3)–H Bond Activation | POLQ, AP3D1, AP3S1 | MAPT 4416/4885MEN1 3613/4885KMT2A 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.