SCHEMBL3681230

SCHEMBL3681230

C=CCc1c[nH]c(SSc2nc(CC=C)c[nH]2)n1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8077429 0.87 ALDH1A1 (0.42) ALDH1A1HPGDMEN1KMT2A
SCHEMBL1076387 0.75 — —
SCHEMBL11285037 0.73 — —
SCHEMBL6673952 0.73 — —
SCHEMBL3806548 0.73 — —
SCHEMBL7487070 0.73 — —
SCHEMBL8020515 0.73 — —
SCHEMBL15543602 0.73 — —
Hydrochloric Acid SCHEMBL16649758 0.73 — —
SCHEMBL370486 0.73 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4365189-A2 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES GENENTECH, INC. (US) 2024-05-08 — — EP claimed
EP-4335863-A2 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES Genentech, Inc. (US) 2024-03-13 — — EP claimed
EP-4245766-A9 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES Genentech, Inc. (US) 2024-01-24 — — EP claimed
EP-4245766-A2 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES Genentech, Inc. (US) 2023-09-20 — — EP claimed
WO-2020028616-A1 METHODS FOR MANUFACTURING RECOMBINANT PROTEIN COMPRISING A DISULFIDE BOND LONZA LTD (CH) 2020-02-06 — — WO claimed
EP-3327026-A1 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES Genentech, Inc. (US) 2018-05-30 — — EP claimed
EP-2188302-B1 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES GENENTECH INC (US) 2017-11-01 — — EP claimed
US-20140128575-A1 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES GENENTECH, INC. (US) 2014-05-08 — — US claimed
EP-2586788-A1 Prevention of disulfide bond reduction during recombinant production of polypeptides Genentech, Inc. (US) 2013-05-01 — — EP claimed
US-20130017598-A1 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES GENENTECH, INC. (US) 2013-01-17 — — US claimed
EP-2188302-A2 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES Genentech, Inc. (US) 2010-05-26 — — EP claimed
US-20090053786-A1 Prevention of disulfide bond reduction during recombinant production of polypeptides GENENTECH, INC. 2009-02-26 — — US claimed
WO-2009009523-A2 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES GENENTECH, INC. (US) 2009-01-15 — — WO claimed
US-11999791-B2 Prevention of disulfide bond reduction during recombinant production of polypeptides GENENTECH, INC. (US) 2024-06-04 — — US disclosed
US-11987638-B1 Prevention of disulfide bond reduction during recombinant production of polypeptides GENENTECH, INC. (US) 2024-05-21 — — US disclosed
US-11987637-B1 Prevention of disulfide bond reduction during recombinant production of polypeptides GENENTECH, INC. (US) 2024-05-21 — — US disclosed
CN-101932591-A Prevention of disulfide bond reduction during recombinant production of polypeptides GENENTECH INC 2010-12-29 — — CN disclosed
EP-2188302-A2 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES Genentech, Inc. (US) 2010-05-26 — — EP disclosed
US-20090053786-A1 Prevention of disulfide bond reduction during recombinant production of polypeptides GENENTECH, INC. 2009-02-26 — — US disclosed
WO-2009009523-A2 PREVENTION OF DISULFIDE BOND REDUCTION DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES GENENTECH, INC. (US) 2009-01-15 — — WO disclosed
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