SCHEMBL3681535

SCHEMBL3681535

C=CCOC([SiH3])=C(OCC=C)OCC=C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694339 0.72
SCHEMBL1162480 0.70
SCHEMBL7650901 0.67 CYP3A4 (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL3317962 0.67
SCHEMBL7646236 0.65 CYP3A4 (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL17870872 0.65
SCHEMBL16553403 0.65
SCHEMBL28706322 0.64 TDP1 (0.34) CYP3A4
SCHEMBL6695619 0.63 CYP3A4 (0.38) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL333050 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3966687-A TRIALKYLOXYVINYLSILANE MANUFACTURE DE PRODUITS CHIMIQUES PROTEX (FR) 1976-06-29 US claimed
WO-2022181545-A1 MANUFACTURING METHOD FOR POLYMER COMPRISING HYDROLYZABLE SILYL GROUP, AND POLYMER, CURABLE COMPOSITION, AND CURED PRODUCT 株式会社カネカ 2022-09-01 WO disclosed
EP-1764118-B1 Polymer coating for medical devices GILEAD PALO ALTO INC (US) 2010-08-25 EP disclosed
EP-1937328-B1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS INC (US) 2009-08-26 EP disclosed
US-7419709-B2 Polymer coating for medical devices CV THERAPEUTICS, INC. (US) 2008-09-02 US disclosed
US-20080160166-A1 POLYMER COATING FOR MEDICAL DEVICES RYPACEK FRANTISEK 2008-07-03 US disclosed
EP-1937328-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2008-07-02 EP disclosed
US-7364768-B2 Polymer coating for medical devices CV THERAPEUTICS, INC. (US) 2008-04-29 US disclosed
WO-2007041972-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2007-04-19 WO disclosed
US-20070071926-A1 Polymer coating for medical devices RYPACEK FRANTISEK 2007-03-29 US disclosed
US-20070071879-A1 Polymer coating for medical devices RYPACEK FRANTISEK 2007-03-29 US disclosed
EP-1764118-A2 Polymer coating for medical devices CV THERAPEUTICS, INC. (US) 2007-03-21 EP disclosed
US-7160592-B2 Polymer coating for medical devices CV THERAPEUTICS, INC. (US) 2007-01-09 US disclosed
EP-1492581-B1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS INC (US) 2006-12-20 EP disclosed
US-20060093771-A1 Polymer coating for medical devices CV THERAPEUTICS, INC. 2006-05-04 US disclosed
EP-1492581-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2005-01-05 EP disclosed
US-20030219562-A1 Polymer coating for medical devices CV THERAPEUTICS, INC. 2003-11-27 US disclosed
WO-2003068289-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2003-08-21 WO disclosed
US-3966687-A TRIALKYLOXYVINYLSILANE MANUFACTURE DE PRODUITS CHIMIQUES PROTEX (FR) 1976-06-29 US disclosed
US-3966687-A TRIALKYLOXYVINYLSILANE MANUFACTURE DE PRODUITS CHIMIQUES PROTEX (FR) 1976-06-29 US disclosed