Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.78 |
| ▸ | NR3C2 | P08235 | 16/20 | 0.62 |
| ▸ | PGR | P06401 | 10/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291665 | 0.88 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL4446023 | 0.86 | NR3C1 (0.59) | NR3C1NR3C2PGR | |
| SCHEMBL3651745 | 0.85 | NR3C1 (0.81) | NR3C1NR3C2PGR | |
| SCHEMBL3945714 | 0.84 | NR3C1 (0.61) | NR3C1NR3C2PGR | |
| SCHEMBL3687823 | 0.83 | NR3C1 (0.78) | NR3C1NR3C2PGR | |
| SCHEMBL3952276 | 0.82 | NR3C1 (0.64) | NR3C1NR3C2PGR | |
| SCHEMBL1932600 | 0.80 | NR3C1 (0.76) | NR3C1NR3C2PGR | |
| SCHEMBL10089058 | 0.79 | NR3C1 (0.85) | NR3C1NR3C2PGR | |
| SCHEMBL379514 | 0.77 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL6387448 | 0.77 | NR3C1 (1.00) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190431-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | Bausch & Lomb Incorporated (US) | 2010-06-02 | — | — | EP | disclosed |
| EP-2051710-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | Bausch & Lomb Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2009023471-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | BAUSCH & LOMB INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |
| WO-2008021729-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | BAUSCH & LOMB INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |