1,4-Butanediol

1,4-Butanediol

SCHEMBL3681996

OC1CCC1O.OCCCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 1/20 0.32
AGL P35573 1/20 0.32
GBA1 P04062 5/20 0.31
PYGL P06737 1/20 0.31
GBA2 Q9HCG7 1/20 0.31
GAA P10253 1/20 0.31
GLB1 P16278 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL28231182 0.87 CA1 (0.41) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
1,5-Pentanediol SCHEMBL2844810 0.84 LMNA (0.36) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
1,6-Hexanediol SCHEMBL1156749 0.84 EPHX1 (0.39) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL17201940 0.82 EPHX1 (0.42) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
1,3-Propanediol SCHEMBL6379474 0.80 CA1 (0.41) TSHRKDM4EGBA1EPHX1
SCHEMBL8508682 0.76 TSHR (0.40) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
1,4-Butanediol SCHEMBL8910988 0.76 TSHR (0.39) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
1,6-Hexanediol SCHEMBL27420700 0.76 TSHR (0.40) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL2568029 0.76
SCHEMBL13889070 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182807-A1 BASE OIL COMPOSITION, FORMULATION AND USE EQUUS UK TOPCO LTD (GB) 2024-06-06 US disclosed
EP-2602273-B1 URETHANE RESIN COMPOSITION, COATING AGENT, URETHANE RESIN COMPOSITION FOR FORMING SURFACE LAYER OF LEATHER-LIKE SHEET, LAMINATE, AND LEATHER-LIKE SHEET DAINIPPON INK & CHEMICALS (JP) 2019-10-23 EP disclosed
US-20150353723-A1 REDUCTION OF BENZYL ALCOHOL EMISSIONS FROM EPOXY AMINE FORMULATIONS BY ADDING CYCLODEXTRIN SIKA TECHNOLOGY AG (CH) 2015-12-10 US disclosed
EP-2602273-A1 URETHANE RESIN COMPOSITION, COATING AGENT, URETHANE RESIN COMPOSITION FOR FORMING SURFACE LAYER OF LEATHER-LIKE SHEET, LAMINATE, AND LEATHER-LIKE SHEET DIC Corporation (JP) 2013-06-12 EP disclosed
US-20130136913-A1 URETHANE RESIN COMPOSITION, COATING AGENT, LAMINATE, AND LEATHER-LIKE SHEET, USE OF URETHANE RESIN COMPOSITION FOR FORMING SURFACE SKIN LAYER OF LEATHER-LIKE SHEET DIC CORPORATION (JP) 2013-05-30 US disclosed
EP-1843715-B1 DEVICE FOR MANDIBULAR ADVANCEMENT QUIESCO PTY LTD (AU) 2013-02-27 EP disclosed
EP-2048188-B1 Masterbatch of polyfunctional compounds usable for producing manufactured articles made of expanded polyester resin B L PLASTIC S R L (IT) 2012-07-11 EP disclosed
US-7841346-B2 Method and device for mandibular advancement QUIESCO PTY. LTD. (AU) 2010-11-30 US disclosed
US-7671142-B2 Thermoplastic resin having rigidity when heated ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-03-02 US disclosed
EP-2048188-A1 Masterbatch of polyfunctional compounds usable for producing manufactured articles made of expanded polyester resin B.L.Plastic S.R.L. (IT) 2009-04-15 EP disclosed
EP-0881091-A2 Recording material Toyo Boseki Kabushiki Kaisha (JP) 1998-12-02 EP disclosed
EP-0739366-B1 REACTIVE DILUENT FOR RADIATION CURING OF FILM-FORMING POLYMERS ISP INVESTMENTS INC (US) 1998-08-05 EP disclosed
EP-0739366-A4 REACTIVE DILUENT FOR RADIATION CURING OF FILM-FORMING POLYMERS ISP INVESTMENTS INC (US) 1997-05-28 EP disclosed
EP-0739366-A1 REACTIVE DILUENT FOR RADIATION CURING OF FILM-FORMING POLYMERS ISP INVESTMENTS INC. (US) 1996-10-30 EP disclosed
EP-0510545-B1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM SPA (IT) 1996-10-02 EP disclosed
US-5468820-A Curing a (meth)acrylate using N-vinyl lactam and noncyclic N-vinyl amide ISP INVESTMENTS INC. (US) 1995-11-21 US disclosed
WO-1995019378-A1 REACTIVE DILUENT FOR RADIATION CURING OF FILM-FORMING POLYMERS ISP INVESTMENTS INC. (US) 1995-07-20 WO disclosed
EP-0510545-A1 Elastomeric thermoplastic copolyetheresters having improved thermal and hydrolytic stabilities ENICHEM S.p.A. (IT) 1992-10-28 EP disclosed
US-4968731-A Glass fiber reinforced thermoplastic molding compositions based on polyesters and graft polymers BASF AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
US-4239882-A DISTILLATION AND REUSE OF 1,4-BUTANEDIOL MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1980-12-16 US disclosed