SCHEMBL3682219

SCHEMBL3682219

C=C(C)C(=O)NCCCCCCBr

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
PAOX Q6QHF9 3/20 0.39
ADRA1A P35348 1/20 0.38
EPHX1 P07099 5/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
PLA2G2A P14555 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.35
FAAH O00519 1/20 0.35
CASP2 P42575 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9948914 0.92 KDM4E (0.39) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL59429 0.89 KDM4E (0.56) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL8775285 0.89 KDM4E (0.56) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL8774992 0.89 KDM4E (0.56) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL8775294 0.89 KDM4E (0.56) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL8775499 0.89 KDM4E (0.56) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL8775297 0.89 KDM4E (0.56) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL907569 0.87 KDM4E (0.52) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL10081668 0.83 KDM4E (0.70) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL8746183 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100298504-A1 AMPHIPHILIC POLYMER AND PROCESSES OF FORMING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-11-25 US disclosed
WO-2009038544-A1 AMPHIPHILIC POLYMER AND PROCESSES OF FORMING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-03-26 WO disclosed
EP-0476187-B1 A highly photosensitive imaging element based on a photosensitive resin AGFA GEVAERT NV (BE) 1998-05-20 EP disclosed
EP-0476187-A1 A highly photosensitive imaging element based on a photosensitive resin AGFA-GEVAERT N.V. (BE) 1992-03-25 EP disclosed