Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775297 | 1.00 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8775285 | 1.00 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8774992 | 1.00 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8775499 | 1.00 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL59429 | 1.00 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL907569 | 0.97 | KDM4E (0.52) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL10081668 | 0.93 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL632876 | 0.92 | KDM4E (0.46) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8218361 | 0.91 | KDM4E (0.48) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL18139435 | 0.91 | KDM4E (0.48) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606742-B1 | Bile acid sequestrant | ROHM & HAAS (US) | 1997-11-19 | — | — | EP | claimed |
| US-5451397-A | Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels | ROHM AND HAAS COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| EP-0606742-A1 | Bile acid sequestrant | ROHM AND HAAS COMPANY (US) | 1994-07-20 | — | — | EP | claimed |
| CN-107057802-B | Glass grinding fluid containing bola type surfactant, preparation method and use method | 泰伦特生物工程股份有限公司 | 2020-12-25 | — | — | CN | disclosed |
| EP-0606742-B1 | Bile acid sequestrant | ROHM & HAAS (US) | 1997-11-19 | — | — | EP | disclosed |
| US-5451397-A | Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels | ROHM AND HAAS COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0606742-A1 | Bile acid sequestrant | ROHM AND HAAS COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |