SCHEMBL36826

SCHEMBL36826

c1ccc(-c2ncncn2)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
NFKB1 P19838 2/20 0.56
NFKB2 Q00653 2/20 0.56
RELA Q04206 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
MAPK1 P28482 1/20 0.52
ATM Q13315 1/20 0.46
HPGDS O60760 8/20 0.45
NOTUM Q6P988 1/20 0.43
POLB P06746 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA2B P29275 1/20 0.42
ADORA1 P30542 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP2A6 P11509 1/20 0.41
NR1H4 Q96RI1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL582179 0.95 NPC1 (0.58) NPC1RAB9ANFKB1NFKB2RELA
Dimethylamine SCHEMBL9804737 0.91 NPC1 (0.48) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL14425836 0.85 NPC1 (0.48) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL27525304 0.85 L3MBTL1 (0.52) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL18327343 0.85 NPC1 (0.48) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL19601156 0.85 NPC1 (0.48) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL18650150 0.85 L3MBTL1 (0.52) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL14425835 0.85 NPC1 (0.48) NPC1RAB9ANFKB1NFKB2RELA
SCHEMBL1421973 0.85 NPC1 (0.40) NPC1RAB9ANFKB1NFKB2RELA
Anthraquinone SCHEMBL27535113 0.85 MEN1 (0.48) NPC1RAB9ANFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3876 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081959-A Preparation method and application of temperature-resistant modified carboxymethyl hydroxypropyl guar gum 广饶六合化工有限公司 2025-06-03 CN claimed
CN-115888400-B Sulfonated porous polymer nanoparticle-metal organic framework composite cation exchange membrane and preparation method thereof 浙江工业大学 2025-05-13 CN claimed
CN-119531210-A Wear-resistant and temperature-resistant artificial lawn and preparation method thereof 江苏赛斯人造草坪有限公司 2025-02-28 CN claimed
CN-118620500-B Phenyl-containing s-triazine ring polyarylether coating for high-temperature resistance and corrosion resistance and preparation method thereof 大连理工大学 2025-02-14 CN claimed
CN-118835339-A Ultraviolet-proof textile fabric and preparation process thereof 江阴泰迪服饰有限公司 2024-10-25 CN claimed
CN-118507126-A High-flame-retardance low-temperature-resistant security fire-proof cable for extremely cold region and production process 浙江光大普特通讯科技股份有限公司 2024-08-16 CN claimed
EP-3898233-B1 FLEXIBLE MULTILAYER FILM WITH UV-VIS BARRIER LAYER FOR MEDICAL PACKAGING POLYCINE GMBH (DE) 2024-04-10 EP claimed
CN-114100373-B Preparation method of polyaniline/triazine polymer nano-composite solvent-resistant nanofiltration membrane 浙江工业大学 2024-04-05 CN claimed
CN-117797869-A Covalent bond-bonded MOFs@COFs composite material and preparation method and application thereof 苏州大学 2024-04-02 CN claimed
CN-117717902-A Preparation method and application of covalent organic framework nanofiltration membrane 天津大学 2024-03-19 CN claimed
US-20030186978-A1 Novel telomerase inhibitors PHARMACIA ITALIA, SPA (IT) 2003-10-02 US claimed
EP-1341856-A1 POLYMER MODIFIED INORGANIC PARTICLES Agrolinz Melamin GmbH (AT) 2003-09-10 EP claimed
EP-1256608-A2 Inkjet inks Hewlett-Packard Company (US) 2002-11-13 EP claimed
WO-2002048270-A1 POLYMER MODIFIED INORGANIC PARTICLES AGROLINZ MELAMIN GMBH (AT) 2002-06-20 WO claimed
WO-2001096339-A1 NOVEL TELOMERASE INHIBITORS PHARMACIA ITALIA S.P.A. (IT) 2001-12-20 WO claimed
US-6239197-B1 TO AN EXTENT SUCH THAT THE BULK DENSITY OF THE POLYMER ADDITIVE IS INCREASED AT LEAST 50% GREAT LAKES CHEMICAL CORPORATION 2001-05-29 US claimed
EP-0466647-B1 Process for the photochemical and thermal stabilisation of polyamide fiber materials CIBA GEIGY AG (CH) 1995-11-29 EP claimed
EP-0310083-B1 PROCESS FOR QUENCHING OR SUPPRESSING THE FLUORESCENCE OF OPTICALLY BRIGHTENED SUBSTRATES CIBA-GEIGY AG (CH) 1993-01-13 EP claimed
US-4950304-A AFTERTREATMENT OR PRETREATMENT OF NYLON TRICOT FABRICS WITH A UV ABSORBER AND FIXING CIBA-GEIGY CORPORATION (US) 1990-08-21 US claimed
EP-0310083-A1 Process for quenching or suppressing the fluorescence of optically brightened substrates CIBA-GEIGY AG (CH) 1989-04-05 EP claimed