Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157817 | 1.00 | CA2 (0.60) | CA2CA1CPB2MAPK1ZDHHC7 | |
| SCHEMBL2334605 | 1.00 | CA2 (0.60) | CA2CA1CPB2MAPK1ZDHHC7 | |
| SCHEMBL6518229 | 1.00 | CA2 (0.60) | CA2CA1CPB2MAPK1ZDHHC7 | |
| SCHEMBL28822842 | 1.00 | CA2 (0.60) | CA2CA1CPB2MAPK1ZDHHC7 | |
| SCHEMBL3671861 | 1.00 | CA2 (0.60) | CA2CA1CPB2MAPK1ZDHHC7 | |
| SCHEMBL5046728 | 1.00 | CA2 (0.60) | CA2CA1CPB2MAPK1ZDHHC7 | |
| SCHEMBL25279786 | 1.00 | CA2 (0.60) | CA2CA1CPB2MAPK1ZDHHC7 | |
| SCHEMBL28547703 | 1.00 | CA2 (0.60) | CA2CA1CPB2MAPK1ZDHHC7 | |
| SCHEMBL5049747 | 1.00 | CA2 (0.60) | CA2CA1CPB2MAPK1ZDHHC7 | |
| Ammonia Solution, Strong SCHEMBL5804627 | 0.98 | CA2 (0.58) | CA2CA1CPB2MAPK1ZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110279684-B | Use of formyl peptide receptor 2 agonists for the treatment of ocular inflammatory diseases | 阿勒根公司 | 2023-02-28 | — | — | CN | claimed |
| CN-112430632-B | Preparation method of 2- ((trans) -4-aminocyclohexyl) isopropanol | 上海合全药物研发有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-109661396-B | Spiro-fused cyclic ureas as ROCK inhibitors | 百时美施贵宝公司 | 2022-07-01 | — | — | CN | claimed |
| CN-112430632-A | Preparation method of 2- ((trans) -4-aminocyclohexyl) isopropanol | 上海合全药物研发有限公司 | 2021-03-02 | — | — | CN | claimed |
| CN-105764902-B | Spiro-compound as tryptophan hydroxylase inhibitor | 卡罗斯制药公司 | 2019-02-15 | — | — | CN | claimed |
| CN-112204009-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117580824-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117466874-A | Preparation method of indole-containing polysubstituted tetrahydrofuran compound | 扬州大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-117377675-A | Bruton's tyrosine kinase degradation agent containing parallel ring or spiro ring | 正大天晴药业集团股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-112204012-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-103547579-B | Fused imidazole derivatives as IDO inhibitors | 新联基因公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-102448955-B | Aminopyrimidine Anticancer Compounds | OSI PHARM INC | 2014-06-18 | — | — | CN | disclosed |
| CN-102448955-A | Aminopyrimidine Anticancer Compounds | OSI PHARM INC | 2012-05-09 | — | — | CN | disclosed |
| US-7714087-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20090137757-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | IMUTA JUNICHI | 2009-05-28 | — | — | US | disclosed |
| EP-1631286-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2007-08-29 | — | — | EP | disclosed |
| EP-1631286-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004110993-A2 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-23 | — | — | WO | disclosed |