Ethion

Ethion

SCHEMBL3683160

CCOP(=S)(OCC)SCSP(=S)(OCC)OCC.O=P(O)(O)CCCl

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 4/20 0.46
TSHR P16473 2/20 0.46
CYP3A4 P08684 2/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
PPARD Q03181 2/20 0.35
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethion SCHEMBL29173186 0.84 ALDH1A1 (0.57) ALDH1A1HSD17B10TSHRCYP3A4MEN1
Ethion SCHEMBL9867249 0.82 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRCYP3A4MEN1
Ethion SCHEMBL10642070 0.80 ALDH1A1 (0.61) ALDH1A1HSD17B10TSHRCYP3A4MEN1
Ethion SCHEMBL28450266 0.80 ALDH1A1 (0.61) ALDH1A1HSD17B10TSHRCYP3A4MEN1
Ethion SCHEMBL9343797 0.78 ALDH1A1 (0.68) ALDH1A1HSD17B10TSHRCYP3A4MEN1
Ethion SCHEMBL26750 0.78 ALDH1A1 (0.68) ALDH1A1HSD17B10TSHRCYP3A4MEN1
Ethion SCHEMBL8388102 0.75 ALDH1A1 (0.65) ALDH1A1HSD17B10TSHRCYP3A4MEN1
Ethion SCHEMBL28489791 0.74 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRCYP3A4MEN1
SCHEMBL5933951 0.74 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRCYP3A4MEN1
Ethion SCHEMBL8081169 0.74 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRCYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010095151-A2 A NOVEL WATER DISPERSIBLE GRANULAR COMPOSITION SHAH DEEPAK PRANJIVANDAS (NA) 2010-08-26 WO claimed
US-10791732-B2 Water dispersible granular composition DEEPAK PRANJIVANDAS SHAH (IN) 2020-10-06 US disclosed
US-20110306502-A1 Novel Water Dispersible Granular Composition SHAH, DEEPAK PRANJIVANDAS (IN) 2011-12-15 US disclosed
WO-2010095151-A2 A NOVEL WATER DISPERSIBLE GRANULAR COMPOSITION SHAH DEEPAK PRANJIVANDAS (NA) 2010-08-26 WO disclosed