Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13550896 | 1.00 | USP2 (0.37) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL20406585 | 0.78 | CHRM2 (0.43) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL483259 | 0.78 | CHRM2 (0.43) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL7609856 | 0.77 | USP2 (0.35) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL17936992 | 0.76 | USP2 (0.39) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL9409739 | 0.73 | KDM4E (0.38) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL22096750 | 0.73 | CHRM2 (0.46) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL19420020 | 0.73 | CHRM2 (0.46) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL23902600 | 0.72 | CHRM2 (0.39) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL21470687 | 0.72 | CHRM2 (0.39) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649094-B2 | Optically active compounds, method for kinetic optical resolution of carboxylic acid derivatives and catalysts therefor | DAISO CO., LTD. (JP) | 2010-01-19 | — | — | US | disclosed |
| US-7649094-B2 | Optically active compounds, method for kinetic optical resolution of carboxylic acid derivatives and catalysts therefor | DAISO CO., LTD. (JP) | 2010-01-19 | — | — | US | disclosed |
| US-7649094-B2 | Optically active compounds, method for kinetic optical resolution of carboxylic acid derivatives and catalysts therefor | DAISO CO., LTD. (JP) | 2010-01-19 | — | — | US | disclosed |
| EP-1477488-B1 | NOVEL OPTICALLY ACTIVE COMPOUNDS, METHOD FOR KINETIC OPTICAL RESOLUTION OF CARBOXYLIC ACID DERIVATIVES AND CATALYSTS THEREFOR | DAISO CO LTD (JP) | 2009-08-26 | — | — | EP | disclosed |
| EP-1477488-B1 | NOVEL OPTICALLY ACTIVE COMPOUNDS, METHOD FOR KINETIC OPTICAL RESOLUTION OF CARBOXYLIC ACID DERIVATIVES AND CATALYSTS THEREFOR | DAISO CO LTD (JP) | 2009-08-26 | — | — | EP | disclosed |
| US-20050154209-A1 | Novel optically active compounds, method for kinetic optical resolution of carboxylic acid derivatives and catalysts therefor | OSAKA SODA CO., LTD. (JP) | 2005-07-14 | — | — | US | disclosed |
| EP-1477488-A1 | NOVEL OPTICALLY ACTIVE COMPOUNDS, METHOD FOR KINETIC OPTICAL RESOLUTION OF CARBOXYLIC ACID DERIVATIVES AND CATALYSTS THEREFOR | DAISO CO., LTD. (JP) | 2004-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154209-A1 | Novel optically active compounds, method for kinetic optical resolution of carboxylic acid derivatives and catalysts therefor | FAR1, TECR, FFAR1 | USP2 4433/4885SMN1; SMN2 3880/4885CHRM2 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.