Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CRAT | P43155 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 3/20 | 0.38 |
| ▸ | CPT1A | P50416 | 3/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3683757 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAL3MBTL1CRAT | |
| SCHEMBL13409928 | 0.91 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAL3MBTL1ACACB | |
| SCHEMBL3686893 | 0.86 | CPT2 (0.45) | CRATCPT2CPT1ACPT1B | |
| SCHEMBL3686891 | 0.86 | CPT2 (0.45) | CRATCPT2CPT1ACPT1B | |
| SCHEMBL3688358 | 0.86 | CRAT (0.40) | ALDH1A1KDM4ELMNAL3MBTL1CRAT | |
| SCHEMBL3688363 | 0.86 | CRAT (0.40) | ALDH1A1KDM4ELMNAL3MBTL1CRAT | |
| SCHEMBL3681659 | 0.82 | CPT2 (0.60) | ACACBCPT2CPT1ACPT1B | |
| SCHEMBL3681655 | 0.82 | CPT2 (0.60) | ACACBCPT2CPT1ACPT1B | |
| SCHEMBL3687169 | 0.82 | CRAT (0.49) | CRAT | |
| SCHEMBL3687172 | 0.82 | CRAT (0.49) | CRAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | ALDH1A1 236/4885KDM4E 1405/4885LMNA 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.