Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 9/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | CMA1 | P23946 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HK1 | P19367 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686408 | 0.93 | PPARD (0.41) | PPARDPPARACMA1 | |
| SCHEMBL13508293 | 0.91 | PFKFB3 (0.37) | ESR1CMA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3685641 | 0.91 | PFKFB3 (0.37) | ESR1CMA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13508363 | 0.90 | F9 (0.36) | ESR1PPARDF9PPARAALDH1A1 | |
| SCHEMBL3694979 | 0.84 | PPARD (0.41) | PPARDPPARACMA1 | |
| SCHEMBL3679124 | 0.84 | PPARD (0.40) | PPARDPPARACMA1 | |
| SCHEMBL13508409 | 0.84 | PPARD (0.40) | PPARDPPARACMA1 | |
| SCHEMBL13508288 | 0.84 | PPARD (0.40) | PPARDPPARACMA1 | |
| SCHEMBL3684587 | 0.83 | PFKFB3 (0.38) | ESR1CMA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3688989 | 0.83 | PFKFB3 (0.38) | ESR1CMA1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| EP-1597248-B1 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | LILLY CO ELI (US) | 2007-12-26 | — | — | EP | disclosed |