Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 1.00 |
| ▸ | ITGAV | P06756 | 20/20 | 1.00 |
| ▸ | ITGA2B | P08514 | 15/20 | 1.00 |
| ▸ | ITGB5 | P18084 | 10/20 | 1.00 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928144 | 0.89 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2954835 | 0.88 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL2902283 | 0.88 | ITGB3 (0.86) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2899642 | 0.87 | ITGB3 (0.84) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL2926965 | 0.86 | ITGB3 (0.87) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2927647 | 0.85 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2905509 | 0.85 | ITGB3 (0.83) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2902730 | 0.85 | ITGB3 (0.83) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL2905344 | 0.85 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL4251938 | 0.85 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539739-B1 | PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-24 | — | — | EP | disclosed |